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Post-Polymerization Modification of Fluoropolymers via UV Irradiation in the Presence of a Photoacid Generator
Fluorinated polymers have unique wettability and protein adsorption properties. The site-specific alteration of these properties could expand their application to different research areas. In this work, a fluorinated homopolymer and two of its copolymers with 4-vinylbenzyl glycidyl ether (VBGE) are...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9919986/ https://www.ncbi.nlm.nih.gov/pubmed/36771794 http://dx.doi.org/10.3390/polym15030493 |
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author | Nika, Anastasia Gkioka, Christina Machairioti, Fotini Bilalis, Panayiotis Xu, Jiaxi Gajos, Katarzyna Awsiuk, Kamil Petrou, Panagiota Chatzichristidi, Margarita |
author_facet | Nika, Anastasia Gkioka, Christina Machairioti, Fotini Bilalis, Panayiotis Xu, Jiaxi Gajos, Katarzyna Awsiuk, Kamil Petrou, Panagiota Chatzichristidi, Margarita |
author_sort | Nika, Anastasia |
collection | PubMed |
description | Fluorinated polymers have unique wettability and protein adsorption properties. The site-specific alteration of these properties could expand their application to different research areas. In this work, a fluorinated homopolymer and two of its copolymers with 4-vinylbenzyl glycidyl ether (VBGE) are synthesized by free radical polymerization. The produced polymers are then used to develop resist formulations by the addition of a photoacid generator. Films of these formulations are exposed to ultraviolet radiation through a binary mask and heated to create the pattern. It is found that the water contact angle values of the exposed films areas are reduced compared to those of the unexposed ones, with the exception of pentafluorophenyl methacrylate (PFMA) homopolymer film. This is attributed to the reaction of the epoxy groups creating x-links and producing hydroxyl groups and the cleavage of the pentafluorophenyl group from the ester group leading to carboxylic acid groups. Both modifications on the exposed areas are verified by FTIR spectroscopy and ToF-SIMS analysis. In addition, the biomolecules adsorption ability of the exposed area is increasing 10–15 times compared to the unexposed one for the PFMA homopolymer and the PFMA/VBGE 1:1 copolymer. Thus, the proposed polymers and patterning procedure could find application to spatially directed immobilization of biomolecules and/or cells onto a surface for both biosensing and tissue engineering purposes. |
format | Online Article Text |
id | pubmed-9919986 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-99199862023-02-12 Post-Polymerization Modification of Fluoropolymers via UV Irradiation in the Presence of a Photoacid Generator Nika, Anastasia Gkioka, Christina Machairioti, Fotini Bilalis, Panayiotis Xu, Jiaxi Gajos, Katarzyna Awsiuk, Kamil Petrou, Panagiota Chatzichristidi, Margarita Polymers (Basel) Article Fluorinated polymers have unique wettability and protein adsorption properties. The site-specific alteration of these properties could expand their application to different research areas. In this work, a fluorinated homopolymer and two of its copolymers with 4-vinylbenzyl glycidyl ether (VBGE) are synthesized by free radical polymerization. The produced polymers are then used to develop resist formulations by the addition of a photoacid generator. Films of these formulations are exposed to ultraviolet radiation through a binary mask and heated to create the pattern. It is found that the water contact angle values of the exposed films areas are reduced compared to those of the unexposed ones, with the exception of pentafluorophenyl methacrylate (PFMA) homopolymer film. This is attributed to the reaction of the epoxy groups creating x-links and producing hydroxyl groups and the cleavage of the pentafluorophenyl group from the ester group leading to carboxylic acid groups. Both modifications on the exposed areas are verified by FTIR spectroscopy and ToF-SIMS analysis. In addition, the biomolecules adsorption ability of the exposed area is increasing 10–15 times compared to the unexposed one for the PFMA homopolymer and the PFMA/VBGE 1:1 copolymer. Thus, the proposed polymers and patterning procedure could find application to spatially directed immobilization of biomolecules and/or cells onto a surface for both biosensing and tissue engineering purposes. MDPI 2023-01-17 /pmc/articles/PMC9919986/ /pubmed/36771794 http://dx.doi.org/10.3390/polym15030493 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Nika, Anastasia Gkioka, Christina Machairioti, Fotini Bilalis, Panayiotis Xu, Jiaxi Gajos, Katarzyna Awsiuk, Kamil Petrou, Panagiota Chatzichristidi, Margarita Post-Polymerization Modification of Fluoropolymers via UV Irradiation in the Presence of a Photoacid Generator |
title | Post-Polymerization Modification of Fluoropolymers via UV Irradiation in the Presence of a Photoacid Generator |
title_full | Post-Polymerization Modification of Fluoropolymers via UV Irradiation in the Presence of a Photoacid Generator |
title_fullStr | Post-Polymerization Modification of Fluoropolymers via UV Irradiation in the Presence of a Photoacid Generator |
title_full_unstemmed | Post-Polymerization Modification of Fluoropolymers via UV Irradiation in the Presence of a Photoacid Generator |
title_short | Post-Polymerization Modification of Fluoropolymers via UV Irradiation in the Presence of a Photoacid Generator |
title_sort | post-polymerization modification of fluoropolymers via uv irradiation in the presence of a photoacid generator |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9919986/ https://www.ncbi.nlm.nih.gov/pubmed/36771794 http://dx.doi.org/10.3390/polym15030493 |
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