Titanium Dioxide/Chromium Oxide/Graphene Oxide Doped into Cellulose Acetate for Medical Applications

Wound dressings have been designed based on cellulose acetate encapsulated with different concentrations of chromium oxide (Cr(2)O(3)) and titanium oxide (TiO(2)) with/without graphene oxide (GO). This study comprises the structural, morphological, optical, thermal, and biological behavior of chromium oxide/titanium dioxide/graphene oxide-integrated cellulose acetate (CA) films. The CA-based film bond formation was introduced by functional group analysis via Fourier transform infrared (FTIR) spectroscopy. The fabricated Cr(2)O(3)/TiO(2)/GO@CA film SEM micrographs demonstrate transition metal oxides Cr(2)O(3) and TiO(2) on a nano-scale. The TiO(2)@CA shows the lowest contact angle with 30°. Optically, the refractive index increases from 1.76 for CA to 2.14 for the TiO(2)@CA film. Moreover, normal lung cells (A138) growth examination in a function of Cr(2)O(3)/TiO(2)/GO@CA film concentration is conducted, introducing 93.46% with the usage of 4.9 µg/mL. The resulting data showed a promising wound-healing behavior of the CA-based films.