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Triglyceride–Glucose Index as a Potential Indicator of Sarcopenic Obesity in Older People

Purpose: This population-based cross-sectional study aimed to determine whether the triglyceride–glucose index (TyG index) is associated with sarcopenic obesity (SO) and whether it would be a helpful indicator of SO. Methods: A total of 3821 participants aged ≥ 60 years were selected for the study g...

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Autores principales: Kim, Bokun, Kim, Gwonmin, Lee, Yongkook, Taniguchi, Keisuke, Isobe, Tomonori, Oh, Sechang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9920571/
https://www.ncbi.nlm.nih.gov/pubmed/36771263
http://dx.doi.org/10.3390/nu15030555
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author Kim, Bokun
Kim, Gwonmin
Lee, Yongkook
Taniguchi, Keisuke
Isobe, Tomonori
Oh, Sechang
author_facet Kim, Bokun
Kim, Gwonmin
Lee, Yongkook
Taniguchi, Keisuke
Isobe, Tomonori
Oh, Sechang
author_sort Kim, Bokun
collection PubMed
description Purpose: This population-based cross-sectional study aimed to determine whether the triglyceride–glucose index (TyG index) is associated with sarcopenic obesity (SO) and whether it would be a helpful indicator of SO. Methods: A total of 3821 participants aged ≥ 60 years were selected for the study group, and 4919 participants aged 20–39 years were included as a reference group. The participants were allocated to sarcopenia, obesity, and SO groups depending on if their body mass index (BMI) was ≥25 kg/m(2) and their sarcopenia index was ≤1 standard deviation (SD) lower than the mean of the reference group. The sex-specific differences and trends among the participants were analyzed by using the TyG index tertiles, and appropriate cut-off values of the TyG index for SO were calculated. Results: As the TyG index increased, BMI increased, but the sarcopenia index decreased in both sexes. Males and females in the middle and highest tertiles of the TyG index were 1.775 and 3.369, and they were 1.993 and 3.157 times more likely to have SO, respectively. The cut-off values of the TyG index for SO in males and females were ≥8.72 and 8.67, respectively. Conclusion: A high TyG index is positively associated with SO, and the TyG index may be considered a potential indicator of SO.
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spelling pubmed-99205712023-02-12 Triglyceride–Glucose Index as a Potential Indicator of Sarcopenic Obesity in Older People Kim, Bokun Kim, Gwonmin Lee, Yongkook Taniguchi, Keisuke Isobe, Tomonori Oh, Sechang Nutrients Article Purpose: This population-based cross-sectional study aimed to determine whether the triglyceride–glucose index (TyG index) is associated with sarcopenic obesity (SO) and whether it would be a helpful indicator of SO. Methods: A total of 3821 participants aged ≥ 60 years were selected for the study group, and 4919 participants aged 20–39 years were included as a reference group. The participants were allocated to sarcopenia, obesity, and SO groups depending on if their body mass index (BMI) was ≥25 kg/m(2) and their sarcopenia index was ≤1 standard deviation (SD) lower than the mean of the reference group. The sex-specific differences and trends among the participants were analyzed by using the TyG index tertiles, and appropriate cut-off values of the TyG index for SO were calculated. Results: As the TyG index increased, BMI increased, but the sarcopenia index decreased in both sexes. Males and females in the middle and highest tertiles of the TyG index were 1.775 and 3.369, and they were 1.993 and 3.157 times more likely to have SO, respectively. The cut-off values of the TyG index for SO in males and females were ≥8.72 and 8.67, respectively. Conclusion: A high TyG index is positively associated with SO, and the TyG index may be considered a potential indicator of SO. MDPI 2023-01-20 /pmc/articles/PMC9920571/ /pubmed/36771263 http://dx.doi.org/10.3390/nu15030555 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Kim, Bokun
Kim, Gwonmin
Lee, Yongkook
Taniguchi, Keisuke
Isobe, Tomonori
Oh, Sechang
Triglyceride–Glucose Index as a Potential Indicator of Sarcopenic Obesity in Older People
title Triglyceride–Glucose Index as a Potential Indicator of Sarcopenic Obesity in Older People
title_full Triglyceride–Glucose Index as a Potential Indicator of Sarcopenic Obesity in Older People
title_fullStr Triglyceride–Glucose Index as a Potential Indicator of Sarcopenic Obesity in Older People
title_full_unstemmed Triglyceride–Glucose Index as a Potential Indicator of Sarcopenic Obesity in Older People
title_short Triglyceride–Glucose Index as a Potential Indicator of Sarcopenic Obesity in Older People
title_sort triglyceride–glucose index as a potential indicator of sarcopenic obesity in older people
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9920571/
https://www.ncbi.nlm.nih.gov/pubmed/36771263
http://dx.doi.org/10.3390/nu15030555
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