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β-Cryptoxanthin Attenuates Cigarette-Smoke-Induced Lung Lesions in the Absence of Carotenoid Cleavage Enzymes (BCO1/BCO2) in Mice

High dietary intake of β-cryptoxanthin (BCX, an oxygenated provitamin A carotenoid) is associated with a lower risk of lung disease in smokers. BCX can be cleaved by β-carotene-15,15′-oxygenase (BCO1) and β-carotene-9′,10′-oxygenase (BCO2) to produce retinol and apo-10′-carotenoids. We investigated...

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Detalles Bibliográficos
Autores principales: Chiaverelli, Rachel A., Hu, Kang-Quan, Liu, Chun, Lim, Ji Ye, Daniels, Michael S., Xia, Hui, Mein, Jonathan, von Lintig, Johannes, Wang, Xiang-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9920649/
https://www.ncbi.nlm.nih.gov/pubmed/36771049
http://dx.doi.org/10.3390/molecules28031383