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Effectiveness of a Lifestyle Change Program on Insulin Resistance in Yaquis Indigenous Populations in Sonora, Mexico: PREVISY
To evaluate the effectiveness of the healthy lifestyle promotion program for Yaquis (PREVISY) on insulin resistance in the short- and medium-term periods in adults who are overweight/obese and have an increased risk for diabetes. Using a translational research design, an intervention program was imp...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9920776/ https://www.ncbi.nlm.nih.gov/pubmed/36771304 http://dx.doi.org/10.3390/nu15030597 |
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author | Castro-Juarez, Alejandro Arturo Serna-Gutiérrez, Araceli Alemán-Mateo, Heliodoro Gallegos-Aguilar, Ana Cristina Dórame-López, Norma Alicia Valenzuela-Sánchez, Abraham Valenzuela-Guzmán, Diana Marcela Díaz-Zavala, Rolando Giovanni Urquidez-Romero, Rene Esparza-Romero, Julián |
author_facet | Castro-Juarez, Alejandro Arturo Serna-Gutiérrez, Araceli Alemán-Mateo, Heliodoro Gallegos-Aguilar, Ana Cristina Dórame-López, Norma Alicia Valenzuela-Sánchez, Abraham Valenzuela-Guzmán, Diana Marcela Díaz-Zavala, Rolando Giovanni Urquidez-Romero, Rene Esparza-Romero, Julián |
author_sort | Castro-Juarez, Alejandro Arturo |
collection | PubMed |
description | To evaluate the effectiveness of the healthy lifestyle promotion program for Yaquis (PREVISY) on insulin resistance in the short- and medium-term periods in adults who are overweight/obese and have an increased risk for diabetes. Using a translational research design, an intervention program was implemented in a sample of 93 Yaqui adult subjects. The effectiveness of PREVISY was evaluated by comparing the levels of Homeostasis Model Assessment of Insulin Resistance (HOMA-IR) and the Triglycerides-Glucose Index (TyG index) at 6 and 12 months using a paired t-test. Results: In the subjects who completed the program, a decrease in the HOMA-IR index (∆ = −0.91 and ∆ = −1.29, p ≤ 0.05) and the TyG index (∆ = −0.24 y ∆ = −0.20, p ≤ 0.05) was observed in the short- and medium-term period, respectively. Subjects with body weight loss ≥ 10% showed decreased levels of HOMA-IR (∆ = −3.32 and ∆ = −4.89, p ≤ 0.05) and the TyG index (∆ = −0.80 and ∆ = −0.60, p ≤ 0.05) at 6 and 12 months, respectively. A stronger benefit of the program was found in subjects with obesity (vs. overweight) and with high and very high risk of diabetes (vs. moderate risk) in IR markers (p ≤ 0.05). The PREVISY program demonstrated its effectiveness in the improvement of some markers of insulin resistance in Yaqui adults at risk of diabetes. |
format | Online Article Text |
id | pubmed-9920776 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-99207762023-02-12 Effectiveness of a Lifestyle Change Program on Insulin Resistance in Yaquis Indigenous Populations in Sonora, Mexico: PREVISY Castro-Juarez, Alejandro Arturo Serna-Gutiérrez, Araceli Alemán-Mateo, Heliodoro Gallegos-Aguilar, Ana Cristina Dórame-López, Norma Alicia Valenzuela-Sánchez, Abraham Valenzuela-Guzmán, Diana Marcela Díaz-Zavala, Rolando Giovanni Urquidez-Romero, Rene Esparza-Romero, Julián Nutrients Article To evaluate the effectiveness of the healthy lifestyle promotion program for Yaquis (PREVISY) on insulin resistance in the short- and medium-term periods in adults who are overweight/obese and have an increased risk for diabetes. Using a translational research design, an intervention program was implemented in a sample of 93 Yaqui adult subjects. The effectiveness of PREVISY was evaluated by comparing the levels of Homeostasis Model Assessment of Insulin Resistance (HOMA-IR) and the Triglycerides-Glucose Index (TyG index) at 6 and 12 months using a paired t-test. Results: In the subjects who completed the program, a decrease in the HOMA-IR index (∆ = −0.91 and ∆ = −1.29, p ≤ 0.05) and the TyG index (∆ = −0.24 y ∆ = −0.20, p ≤ 0.05) was observed in the short- and medium-term period, respectively. Subjects with body weight loss ≥ 10% showed decreased levels of HOMA-IR (∆ = −3.32 and ∆ = −4.89, p ≤ 0.05) and the TyG index (∆ = −0.80 and ∆ = −0.60, p ≤ 0.05) at 6 and 12 months, respectively. A stronger benefit of the program was found in subjects with obesity (vs. overweight) and with high and very high risk of diabetes (vs. moderate risk) in IR markers (p ≤ 0.05). The PREVISY program demonstrated its effectiveness in the improvement of some markers of insulin resistance in Yaqui adults at risk of diabetes. MDPI 2023-01-23 /pmc/articles/PMC9920776/ /pubmed/36771304 http://dx.doi.org/10.3390/nu15030597 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Castro-Juarez, Alejandro Arturo Serna-Gutiérrez, Araceli Alemán-Mateo, Heliodoro Gallegos-Aguilar, Ana Cristina Dórame-López, Norma Alicia Valenzuela-Sánchez, Abraham Valenzuela-Guzmán, Diana Marcela Díaz-Zavala, Rolando Giovanni Urquidez-Romero, Rene Esparza-Romero, Julián Effectiveness of a Lifestyle Change Program on Insulin Resistance in Yaquis Indigenous Populations in Sonora, Mexico: PREVISY |
title | Effectiveness of a Lifestyle Change Program on Insulin Resistance in Yaquis Indigenous Populations in Sonora, Mexico: PREVISY |
title_full | Effectiveness of a Lifestyle Change Program on Insulin Resistance in Yaquis Indigenous Populations in Sonora, Mexico: PREVISY |
title_fullStr | Effectiveness of a Lifestyle Change Program on Insulin Resistance in Yaquis Indigenous Populations in Sonora, Mexico: PREVISY |
title_full_unstemmed | Effectiveness of a Lifestyle Change Program on Insulin Resistance in Yaquis Indigenous Populations in Sonora, Mexico: PREVISY |
title_short | Effectiveness of a Lifestyle Change Program on Insulin Resistance in Yaquis Indigenous Populations in Sonora, Mexico: PREVISY |
title_sort | effectiveness of a lifestyle change program on insulin resistance in yaquis indigenous populations in sonora, mexico: previsy |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9920776/ https://www.ncbi.nlm.nih.gov/pubmed/36771304 http://dx.doi.org/10.3390/nu15030597 |
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