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Effectiveness of a Lifestyle Change Program on Insulin Resistance in Yaquis Indigenous Populations in Sonora, Mexico: PREVISY

To evaluate the effectiveness of the healthy lifestyle promotion program for Yaquis (PREVISY) on insulin resistance in the short- and medium-term periods in adults who are overweight/obese and have an increased risk for diabetes. Using a translational research design, an intervention program was imp...

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Autores principales: Castro-Juarez, Alejandro Arturo, Serna-Gutiérrez, Araceli, Alemán-Mateo, Heliodoro, Gallegos-Aguilar, Ana Cristina, Dórame-López, Norma Alicia, Valenzuela-Sánchez, Abraham, Valenzuela-Guzmán, Diana Marcela, Díaz-Zavala, Rolando Giovanni, Urquidez-Romero, Rene, Esparza-Romero, Julián
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9920776/
https://www.ncbi.nlm.nih.gov/pubmed/36771304
http://dx.doi.org/10.3390/nu15030597
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author Castro-Juarez, Alejandro Arturo
Serna-Gutiérrez, Araceli
Alemán-Mateo, Heliodoro
Gallegos-Aguilar, Ana Cristina
Dórame-López, Norma Alicia
Valenzuela-Sánchez, Abraham
Valenzuela-Guzmán, Diana Marcela
Díaz-Zavala, Rolando Giovanni
Urquidez-Romero, Rene
Esparza-Romero, Julián
author_facet Castro-Juarez, Alejandro Arturo
Serna-Gutiérrez, Araceli
Alemán-Mateo, Heliodoro
Gallegos-Aguilar, Ana Cristina
Dórame-López, Norma Alicia
Valenzuela-Sánchez, Abraham
Valenzuela-Guzmán, Diana Marcela
Díaz-Zavala, Rolando Giovanni
Urquidez-Romero, Rene
Esparza-Romero, Julián
author_sort Castro-Juarez, Alejandro Arturo
collection PubMed
description To evaluate the effectiveness of the healthy lifestyle promotion program for Yaquis (PREVISY) on insulin resistance in the short- and medium-term periods in adults who are overweight/obese and have an increased risk for diabetes. Using a translational research design, an intervention program was implemented in a sample of 93 Yaqui adult subjects. The effectiveness of PREVISY was evaluated by comparing the levels of Homeostasis Model Assessment of Insulin Resistance (HOMA-IR) and the Triglycerides-Glucose Index (TyG index) at 6 and 12 months using a paired t-test. Results: In the subjects who completed the program, a decrease in the HOMA-IR index (∆ = −0.91 and ∆ = −1.29, p ≤ 0.05) and the TyG index (∆ = −0.24 y ∆ = −0.20, p ≤ 0.05) was observed in the short- and medium-term period, respectively. Subjects with body weight loss ≥ 10% showed decreased levels of HOMA-IR (∆ = −3.32 and ∆ = −4.89, p ≤ 0.05) and the TyG index (∆ = −0.80 and ∆ = −0.60, p ≤ 0.05) at 6 and 12 months, respectively. A stronger benefit of the program was found in subjects with obesity (vs. overweight) and with high and very high risk of diabetes (vs. moderate risk) in IR markers (p ≤ 0.05). The PREVISY program demonstrated its effectiveness in the improvement of some markers of insulin resistance in Yaqui adults at risk of diabetes.
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spelling pubmed-99207762023-02-12 Effectiveness of a Lifestyle Change Program on Insulin Resistance in Yaquis Indigenous Populations in Sonora, Mexico: PREVISY Castro-Juarez, Alejandro Arturo Serna-Gutiérrez, Araceli Alemán-Mateo, Heliodoro Gallegos-Aguilar, Ana Cristina Dórame-López, Norma Alicia Valenzuela-Sánchez, Abraham Valenzuela-Guzmán, Diana Marcela Díaz-Zavala, Rolando Giovanni Urquidez-Romero, Rene Esparza-Romero, Julián Nutrients Article To evaluate the effectiveness of the healthy lifestyle promotion program for Yaquis (PREVISY) on insulin resistance in the short- and medium-term periods in adults who are overweight/obese and have an increased risk for diabetes. Using a translational research design, an intervention program was implemented in a sample of 93 Yaqui adult subjects. The effectiveness of PREVISY was evaluated by comparing the levels of Homeostasis Model Assessment of Insulin Resistance (HOMA-IR) and the Triglycerides-Glucose Index (TyG index) at 6 and 12 months using a paired t-test. Results: In the subjects who completed the program, a decrease in the HOMA-IR index (∆ = −0.91 and ∆ = −1.29, p ≤ 0.05) and the TyG index (∆ = −0.24 y ∆ = −0.20, p ≤ 0.05) was observed in the short- and medium-term period, respectively. Subjects with body weight loss ≥ 10% showed decreased levels of HOMA-IR (∆ = −3.32 and ∆ = −4.89, p ≤ 0.05) and the TyG index (∆ = −0.80 and ∆ = −0.60, p ≤ 0.05) at 6 and 12 months, respectively. A stronger benefit of the program was found in subjects with obesity (vs. overweight) and with high and very high risk of diabetes (vs. moderate risk) in IR markers (p ≤ 0.05). The PREVISY program demonstrated its effectiveness in the improvement of some markers of insulin resistance in Yaqui adults at risk of diabetes. MDPI 2023-01-23 /pmc/articles/PMC9920776/ /pubmed/36771304 http://dx.doi.org/10.3390/nu15030597 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Castro-Juarez, Alejandro Arturo
Serna-Gutiérrez, Araceli
Alemán-Mateo, Heliodoro
Gallegos-Aguilar, Ana Cristina
Dórame-López, Norma Alicia
Valenzuela-Sánchez, Abraham
Valenzuela-Guzmán, Diana Marcela
Díaz-Zavala, Rolando Giovanni
Urquidez-Romero, Rene
Esparza-Romero, Julián
Effectiveness of a Lifestyle Change Program on Insulin Resistance in Yaquis Indigenous Populations in Sonora, Mexico: PREVISY
title Effectiveness of a Lifestyle Change Program on Insulin Resistance in Yaquis Indigenous Populations in Sonora, Mexico: PREVISY
title_full Effectiveness of a Lifestyle Change Program on Insulin Resistance in Yaquis Indigenous Populations in Sonora, Mexico: PREVISY
title_fullStr Effectiveness of a Lifestyle Change Program on Insulin Resistance in Yaquis Indigenous Populations in Sonora, Mexico: PREVISY
title_full_unstemmed Effectiveness of a Lifestyle Change Program on Insulin Resistance in Yaquis Indigenous Populations in Sonora, Mexico: PREVISY
title_short Effectiveness of a Lifestyle Change Program on Insulin Resistance in Yaquis Indigenous Populations in Sonora, Mexico: PREVISY
title_sort effectiveness of a lifestyle change program on insulin resistance in yaquis indigenous populations in sonora, mexico: previsy
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9920776/
https://www.ncbi.nlm.nih.gov/pubmed/36771304
http://dx.doi.org/10.3390/nu15030597
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