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Enhanced Ionic Polymer–Metal Composites with Nanocomposite Electrodes for Restoring Eyelid Movement of Patients with Ptosis

The present study aims to use enhanced ionic polymer–metal composites (IPMC) as an artificial muscle (a soft-active actuator) to restore eyelid movement of patients with ptosis. The previous eyelid movement mechanisms contained drawbacks, specifically in the lower eyelid. We used finite element anal...

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Autores principales: Hosseini, Sara Sadat, Yamini, Bakhtiar, Ichkitidze, Levan, Asadi, Majid, Fernandez, Julie, Gholampour, Seifollah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9920823/
https://www.ncbi.nlm.nih.gov/pubmed/36770434
http://dx.doi.org/10.3390/nano13030473
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author Hosseini, Sara Sadat
Yamini, Bakhtiar
Ichkitidze, Levan
Asadi, Majid
Fernandez, Julie
Gholampour, Seifollah
author_facet Hosseini, Sara Sadat
Yamini, Bakhtiar
Ichkitidze, Levan
Asadi, Majid
Fernandez, Julie
Gholampour, Seifollah
author_sort Hosseini, Sara Sadat
collection PubMed
description The present study aims to use enhanced ionic polymer–metal composites (IPMC) as an artificial muscle (a soft-active actuator) to restore eyelid movement of patients with ptosis. The previous eyelid movement mechanisms contained drawbacks, specifically in the lower eyelid. We used finite element analysis (FEA) to find the optimal mechanism among two different models (A and B). In addition to common electrodes of IPMC (gold and platinum), the bovine serum albumin (BSA) and microcrystalline cellulose (MCC) polymers, with optimal weight percentages of carbon nanotube (CNT) nanofiller, were also utilized as non-metallic electrodes to improve the efficiency of the IPMC actuator. In both models, IPMC with nanocomposite electrodes had higher efficiency as compared to the metallic electrodes. In model A, which moved eyelids indirectly, IPMC with MCC-CNT electrode generated a higher force (25.4%) and less stress (5.9 times) as compared to IPMC with BSA-CNT electrode. However, the use of model A (even with IPMCs) with nanocomposite electrodes can have limitations such as possible malposition issues in the eyelids (especially lower). IPMC with MCC-CNT nanocomposite electrode under model B, which moved eyelids directly, was the most efficient option to restore eyelid movement. It led to higher displacements and lower mechanical stress damage as compared to the BSA-CNT. This finding may provide surgeons with valuable data to open a window in the treatment of patients with ptosis.
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spelling pubmed-99208232023-02-12 Enhanced Ionic Polymer–Metal Composites with Nanocomposite Electrodes for Restoring Eyelid Movement of Patients with Ptosis Hosseini, Sara Sadat Yamini, Bakhtiar Ichkitidze, Levan Asadi, Majid Fernandez, Julie Gholampour, Seifollah Nanomaterials (Basel) Article The present study aims to use enhanced ionic polymer–metal composites (IPMC) as an artificial muscle (a soft-active actuator) to restore eyelid movement of patients with ptosis. The previous eyelid movement mechanisms contained drawbacks, specifically in the lower eyelid. We used finite element analysis (FEA) to find the optimal mechanism among two different models (A and B). In addition to common electrodes of IPMC (gold and platinum), the bovine serum albumin (BSA) and microcrystalline cellulose (MCC) polymers, with optimal weight percentages of carbon nanotube (CNT) nanofiller, were also utilized as non-metallic electrodes to improve the efficiency of the IPMC actuator. In both models, IPMC with nanocomposite electrodes had higher efficiency as compared to the metallic electrodes. In model A, which moved eyelids indirectly, IPMC with MCC-CNT electrode generated a higher force (25.4%) and less stress (5.9 times) as compared to IPMC with BSA-CNT electrode. However, the use of model A (even with IPMCs) with nanocomposite electrodes can have limitations such as possible malposition issues in the eyelids (especially lower). IPMC with MCC-CNT nanocomposite electrode under model B, which moved eyelids directly, was the most efficient option to restore eyelid movement. It led to higher displacements and lower mechanical stress damage as compared to the BSA-CNT. This finding may provide surgeons with valuable data to open a window in the treatment of patients with ptosis. MDPI 2023-01-24 /pmc/articles/PMC9920823/ /pubmed/36770434 http://dx.doi.org/10.3390/nano13030473 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Hosseini, Sara Sadat
Yamini, Bakhtiar
Ichkitidze, Levan
Asadi, Majid
Fernandez, Julie
Gholampour, Seifollah
Enhanced Ionic Polymer–Metal Composites with Nanocomposite Electrodes for Restoring Eyelid Movement of Patients with Ptosis
title Enhanced Ionic Polymer–Metal Composites with Nanocomposite Electrodes for Restoring Eyelid Movement of Patients with Ptosis
title_full Enhanced Ionic Polymer–Metal Composites with Nanocomposite Electrodes for Restoring Eyelid Movement of Patients with Ptosis
title_fullStr Enhanced Ionic Polymer–Metal Composites with Nanocomposite Electrodes for Restoring Eyelid Movement of Patients with Ptosis
title_full_unstemmed Enhanced Ionic Polymer–Metal Composites with Nanocomposite Electrodes for Restoring Eyelid Movement of Patients with Ptosis
title_short Enhanced Ionic Polymer–Metal Composites with Nanocomposite Electrodes for Restoring Eyelid Movement of Patients with Ptosis
title_sort enhanced ionic polymer–metal composites with nanocomposite electrodes for restoring eyelid movement of patients with ptosis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9920823/
https://www.ncbi.nlm.nih.gov/pubmed/36770434
http://dx.doi.org/10.3390/nano13030473
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