Chloroquine-Based Mitochondrial ATP Inhibitors

Mitochondria is an important drug target for ailments ranging from neoplastic to neurodegenerative diseases and metabolic diseases. Here, we describe the synthesis of chloroquine analogs and show the results of mitochondrial ATP inhibition testing. The 2,4-dinitrobenzene-based analogs showed concent...

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Detalles Bibliográficos
Autores principales: Wang, Zhiguo, Sheaff, Robert J., Hussaini, Syed R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9920964/
https://www.ncbi.nlm.nih.gov/pubmed/36770828
http://dx.doi.org/10.3390/molecules28031161

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9920964/
https://www.ncbi.nlm.nih.gov/pubmed/36770828
http://dx.doi.org/10.3390/molecules28031161

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