Synthesis of Oleanolic Acid-Dithiocarbamate Conjugates and Evaluation of Their Broad-Spectrum Antitumor Activities

Efficient and mild synthetic routes for bioactive natural product derivatives are of current interest for drug discovery. Herein, on the basis of the pharmacophore hybrid strategy, we report a two-step protocol to obtain a series of structurally novel oleanolic acid (OA)-dithiocarbamate conjugates i...

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Detalles Bibliográficos
Autores principales: Tang, Liyao, Zhang, Yan, Xu, Jinrun, Yang, Qingfan, Du, Fukuan, Wu, Xu, Li, Mingxing, Shen, Jing, Deng, Shuai, Zhao, Yueshui, Xiao, Zhangang, Chen, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9920998/
https://www.ncbi.nlm.nih.gov/pubmed/36771080
http://dx.doi.org/10.3390/molecules28031414

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9920998/
https://www.ncbi.nlm.nih.gov/pubmed/36771080
http://dx.doi.org/10.3390/molecules28031414

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