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Site-Specific Antibody Conjugation with Payloads beyond Cytotoxins
As antibody–drug conjugates have become a very important modality for cancer therapy, many site-specific conjugation approaches have been developed for generating homogenous molecules. The selective antibody coupling is achieved through antibody engineering by introducing specific amino acid or unna...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9921355/ https://www.ncbi.nlm.nih.gov/pubmed/36770585 http://dx.doi.org/10.3390/molecules28030917 |