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Site-Specific Antibody Conjugation with Payloads beyond Cytotoxins

As antibody–drug conjugates have become a very important modality for cancer therapy, many site-specific conjugation approaches have been developed for generating homogenous molecules. The selective antibody coupling is achieved through antibody engineering by introducing specific amino acid or unna...

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Detalles Bibliográficos
Autor principal: Zhou, Qun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9921355/
https://www.ncbi.nlm.nih.gov/pubmed/36770585
http://dx.doi.org/10.3390/molecules28030917