Synthesis of New Azetidine and Oxetane Amino Acid Derivatives through Aza-Michael Addition of NH-Heterocycles with Methyl 2-(Azetidin- or Oxetan-3-Ylidene)Acetates

In this paper, a simple and efficient synthetic route for the preparation of new heterocyclic amino acid derivatives containing azetidine and oxetane rings was described. The starting (N-Boc-azetidin-3-ylidene)acetate was obtained from (N-Boc)azetidin-3-one by the DBU-catalysed Horner–Wadsworth–Emmo...

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Detalles Bibliográficos
Autores principales: Gudelis, Emilis, Krikštolaitytė, Sonata, Stančiauskaitė, Monika, Šachlevičiūtė, Urtė, Bieliauskas, Aurimas, Milišiūnaitė, Vaida, Jankauskas, Rokas, Kleizienė, Neringa, Sløk, Frank A., Šačkus, Algirdas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9921373/
https://www.ncbi.nlm.nih.gov/pubmed/36770762
http://dx.doi.org/10.3390/molecules28031091

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