Synthesis of Novel 1-Oxo-2,3,4-trisubstituted Tetrahydroisoquinoline Derivatives, Bearing Other Heterocyclic Moieties and Comparative Preliminary Study of Anti-Coronavirus Activity of Selected Compounds

A series of novel 1-oxo-2,3,4-trisubstituted tetrahydroisoquinoline (THIQ) derivatives bearing other heterocyclic moieties in their structure were synthesized based on the reaction between homophthalic anhydride and imines. Initial studies were carried out to establish the anti-coronavirus activity...

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Detalles Bibliográficos
Autores principales: Kandinska, Meglena I., Burdzhiev, Nikola T., Cheshmedzhieva, Diana V., Ilieva, Sonia V., Grozdanov, Peter P., Vilhelmova-Ilieva, Neli, Nikolova, Nadya, Lozanova, Vesela V., Nikolova, Ivanka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9921785/
https://www.ncbi.nlm.nih.gov/pubmed/36771170
http://dx.doi.org/10.3390/molecules28031495

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9921785/
https://www.ncbi.nlm.nih.gov/pubmed/36771170
http://dx.doi.org/10.3390/molecules28031495

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