The Use of Anhydrous Barium Hydroxide for Selective Alkylation of Dialkyloxy-tert-butyl-calix[4]arenes

A practical method of selective alkylation of the third hydroxyl group of disubstituted tert-butyl-calix[4]arenes using anhydrous barium hydroxide as a base was developed in this study. The use of this method in the synthesis of inherently chiral derivatives is shown herein.

Detalles Bibliográficos
Autores principales: Yesypenko, Oleksandr A., Trybrat, Oleksandr O., Kalchenko, Vitaly I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9921822/
https://www.ncbi.nlm.nih.gov/pubmed/36770756
http://dx.doi.org/10.3390/molecules28031089
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author Yesypenko, Oleksandr A.
Trybrat, Oleksandr O.
Kalchenko, Vitaly I.
author_facet Yesypenko, Oleksandr A.
Trybrat, Oleksandr O.
Kalchenko, Vitaly I.
author_sort Yesypenko, Oleksandr A.
collection PubMed
description A practical method of selective alkylation of the third hydroxyl group of disubstituted tert-butyl-calix[4]arenes using anhydrous barium hydroxide as a base was developed in this study. The use of this method in the synthesis of inherently chiral derivatives is shown herein.
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spelling pubmed-99218222023-02-12 The Use of Anhydrous Barium Hydroxide for Selective Alkylation of Dialkyloxy-tert-butyl-calix[4]arenes Yesypenko, Oleksandr A. Trybrat, Oleksandr O. Kalchenko, Vitaly I. Molecules Article A practical method of selective alkylation of the third hydroxyl group of disubstituted tert-butyl-calix[4]arenes using anhydrous barium hydroxide as a base was developed in this study. The use of this method in the synthesis of inherently chiral derivatives is shown herein. MDPI 2023-01-21 /pmc/articles/PMC9921822/ /pubmed/36770756 http://dx.doi.org/10.3390/molecules28031089 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Yesypenko, Oleksandr A.
Trybrat, Oleksandr O.
Kalchenko, Vitaly I.
The Use of Anhydrous Barium Hydroxide for Selective Alkylation of Dialkyloxy-tert-butyl-calix[4]arenes
title The Use of Anhydrous Barium Hydroxide for Selective Alkylation of Dialkyloxy-tert-butyl-calix[4]arenes
title_full The Use of Anhydrous Barium Hydroxide for Selective Alkylation of Dialkyloxy-tert-butyl-calix[4]arenes
title_fullStr The Use of Anhydrous Barium Hydroxide for Selective Alkylation of Dialkyloxy-tert-butyl-calix[4]arenes
title_full_unstemmed The Use of Anhydrous Barium Hydroxide for Selective Alkylation of Dialkyloxy-tert-butyl-calix[4]arenes
title_short The Use of Anhydrous Barium Hydroxide for Selective Alkylation of Dialkyloxy-tert-butyl-calix[4]arenes
title_sort use of anhydrous barium hydroxide for selective alkylation of dialkyloxy-tert-butyl-calix[4]arenes
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9921822/
https://www.ncbi.nlm.nih.gov/pubmed/36770756
http://dx.doi.org/10.3390/molecules28031089
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