K(2)CO(3)-Promoted Formal [3+3]-Cycloaddition of N-Unsubstituted Isatin N,N′-Cyclic Azomethine Imine 1,3-Dipoles with Knoevenagel Adducts

The synthesis of dicyclic spiropyridazine oxoindole derivatives by using [3+3]-cycloaddition of N-unsubstituted isatin N,N′-cyclic azomethine imine 1,3-dipoles was reported. The products bearing two consecutive stereocenters, including spiroquaternary stereocenters in one ring structure, can be effe...

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Detalles Bibliográficos
Autores principales: Yang, Guosheng, Li, Sicheng, Wang, Qiumi, Chen, Huabao, Yang, Chunping, Yin, Zhongqiong, Song, Xu, Zhang, Li, Lu, Cuifen, Yue, Guizhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9921867/
https://www.ncbi.nlm.nih.gov/pubmed/36770700
http://dx.doi.org/10.3390/molecules28031034

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