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Towards Developing Novel Prostate Cancer Recurrence Suppressors: Acute Toxicity of Pseurotin A, an Orally Active PCSK9 Axis-Targeting Small-Molecule in Swiss Albino Mice
The proprotein convertase subtilisin kexin type 9 (PCSK9) emerged as a molecular target of great interest for the management of cardiovascular disorders due to its ability to reduce low density lipoprotein (LDL) cholesterol by binding and targeting at LDLR for lysosomal degradation in cells. Prelimi...
Autores principales: | McGehee, Oliver C., Ebrahim, Hassan Y., Rad, Ashkan H., Abdelwahed, Khaldoun S., Mudhish, Ethar A., King, Judy A., Helal, Iman E., Meyer, Sharon A., El Sayed, Khalid A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9922019/ https://www.ncbi.nlm.nih.gov/pubmed/36771126 http://dx.doi.org/10.3390/molecules28031460 |
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