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Spinal Adhesive Arachnoiditis: A Literature Review
Adhesive arachnoiditis (AA) is a rare inflammatory and scar-forming disease with several etiologies that may lead to incapacitating sequelae if not managed early. Nevertheless, as the onset of symptoms varies from days to years, the etiology is not often discovered. The disease is characterized by a...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9922032/ https://www.ncbi.nlm.nih.gov/pubmed/36788823 http://dx.doi.org/10.7759/cureus.33697 |
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author | Maillard, Jadhe Batista, Sávio Medeiros, Felipe Farid, Gabriela Santa Maria, Paulo Eduardo Perret, Caio M Koester, Stefan W Bertani, Raphael |
author_facet | Maillard, Jadhe Batista, Sávio Medeiros, Felipe Farid, Gabriela Santa Maria, Paulo Eduardo Perret, Caio M Koester, Stefan W Bertani, Raphael |
author_sort | Maillard, Jadhe |
collection | PubMed |
description | Adhesive arachnoiditis (AA) is a rare inflammatory and scar-forming disease with several etiologies that may lead to incapacitating sequelae if not managed early. Nevertheless, as the onset of symptoms varies from days to years, the etiology is not often discovered. The disease is characterized by adhesions disrupting the cerebrospinal fluid flow and causing encapsulation and atrophy of the nerve root. Therefore, a range of clinical features may be present, including urinary, gastroenterology, dermatologic, and neurologic. In terms of diagnosis, magnetic resonance imaging is the gold standard showing pseudocysts with adherent and narrow nerve roots toward the center of the dural sac or peripherally cluster and narrow nerve roots with empty thecal sac. Despite its sensitivity and specificity, the imaging findings are not often associated with clinical manifestations, requiring treatment being based on anamneses and clinical findings. Nowadays, AA can be managed with pharmacological and non-pharmacological treatment, although none provides a completely satisfying result. |
format | Online Article Text |
id | pubmed-9922032 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-99220322023-02-13 Spinal Adhesive Arachnoiditis: A Literature Review Maillard, Jadhe Batista, Sávio Medeiros, Felipe Farid, Gabriela Santa Maria, Paulo Eduardo Perret, Caio M Koester, Stefan W Bertani, Raphael Cureus Anesthesiology Adhesive arachnoiditis (AA) is a rare inflammatory and scar-forming disease with several etiologies that may lead to incapacitating sequelae if not managed early. Nevertheless, as the onset of symptoms varies from days to years, the etiology is not often discovered. The disease is characterized by adhesions disrupting the cerebrospinal fluid flow and causing encapsulation and atrophy of the nerve root. Therefore, a range of clinical features may be present, including urinary, gastroenterology, dermatologic, and neurologic. In terms of diagnosis, magnetic resonance imaging is the gold standard showing pseudocysts with adherent and narrow nerve roots toward the center of the dural sac or peripherally cluster and narrow nerve roots with empty thecal sac. Despite its sensitivity and specificity, the imaging findings are not often associated with clinical manifestations, requiring treatment being based on anamneses and clinical findings. Nowadays, AA can be managed with pharmacological and non-pharmacological treatment, although none provides a completely satisfying result. Cureus 2023-01-12 /pmc/articles/PMC9922032/ /pubmed/36788823 http://dx.doi.org/10.7759/cureus.33697 Text en Copyright © 2023, Maillard et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Anesthesiology Maillard, Jadhe Batista, Sávio Medeiros, Felipe Farid, Gabriela Santa Maria, Paulo Eduardo Perret, Caio M Koester, Stefan W Bertani, Raphael Spinal Adhesive Arachnoiditis: A Literature Review |
title | Spinal Adhesive Arachnoiditis: A Literature Review |
title_full | Spinal Adhesive Arachnoiditis: A Literature Review |
title_fullStr | Spinal Adhesive Arachnoiditis: A Literature Review |
title_full_unstemmed | Spinal Adhesive Arachnoiditis: A Literature Review |
title_short | Spinal Adhesive Arachnoiditis: A Literature Review |
title_sort | spinal adhesive arachnoiditis: a literature review |
topic | Anesthesiology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9922032/ https://www.ncbi.nlm.nih.gov/pubmed/36788823 http://dx.doi.org/10.7759/cureus.33697 |
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