Distinct tissue niches direct lung immunopathology via CCL18 and CCL21 in severe COVID-19

Prolonged lung pathology has been associated with COVID-19, yet the cellular and molecular mechanisms behind this chronic inflammatory disease are poorly understood. In this study, we combine advanced imaging and spatial transcriptomics to shed light on the local immune response in severe COVID-19....

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Detalles Bibliográficos
Autores principales: Mothes, Ronja, Pascual-Reguant, Anna, Koehler, Ralf, Liebeskind, Juliane, Liebheit, Alina, Bauherr, Sandy, Philipsen, Lars, Dittmayer, Carsten, Laue, Michael, von Manitius, Regina, Elezkurtaj, Sefer, Durek, Pawel, Heinrich, Frederik, Heinz, Gitta A., Guerra, Gabriela M., Obermayer, Benedikt, Meinhardt, Jenny, Ihlow, Jana, Radke, Josefine, Heppner, Frank L., Enghard, Philipp, Stockmann, Helena, Aschman, Tom, Schneider, Julia, Corman, Victor M., Sander, Leif E., Mashreghi, Mir-Farzin, Conrad, Thomas, Hocke, Andreas C., Niesner, Raluca A., Radbruch, Helena, Hauser, Anja E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9922044/
https://www.ncbi.nlm.nih.gov/pubmed/36774347
http://dx.doi.org/10.1038/s41467-023-36333-2

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