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Dietary exposure to acrylamide of university students in Ningxia of Northwest China and the effect on their neurobehavioral performance and oxidative stress in serum

This study aims to investigate dietary exposure to acrylamide (AA) and also make an assessment of its effect on the neurobehavioral performance and oxidative stress in the serum of university students in Ningxia. The place primarily consists of arid, dry desert, and wheat‐based foods are the staple...

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Autores principales: Gao, Qinghan, Xue, Yanzhong, Yuan, Xiao, Gao, Hua, Wu, Chunsen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9922127/
https://www.ncbi.nlm.nih.gov/pubmed/36789069
http://dx.doi.org/10.1002/fsn3.3101
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author Gao, Qinghan
Xue, Yanzhong
Yuan, Xiao
Gao, Hua
Wu, Chunsen
author_facet Gao, Qinghan
Xue, Yanzhong
Yuan, Xiao
Gao, Hua
Wu, Chunsen
author_sort Gao, Qinghan
collection PubMed
description This study aims to investigate dietary exposure to acrylamide (AA) and also make an assessment of its effect on the neurobehavioral performance and oxidative stress in the serum of university students in Ningxia. The place primarily consists of arid, dry desert, and wheat‐based foods are the staple food there. A total of 803 university students in Ningxia participated in this cross‐sectional study. Diet intake of AA was estimated with FFQ. The AA risk was calculated as margin of exposure (MOE) values. NCTB questionnaires were used to assess neurobehavioral performance. The serum oxidative stress levels of the university students were measured as GSH, MDA, and SOD. The mean for AA exposure of university students was 0.515 μg kg(−1) bw day(−1). The highest contributor was traditional Chinese grain products, representing 34.71% of the total daily AA intake. Followed were deep‐fried potato products, traditional Western grain products, soft drinks, and nuts, which accounted for 23.87%, 16.59%, 11.15%, and 11%, respectively. The median AA exposure were 480 (BMDL(10) = 0.18 mg kg(−1) bw day(−1)) and 827 (BMDL(10) = 0.31 mg kg(−1) bw day(−1)), respectively. The results indicated that diet AA may have an effect on the emotional status and neurobehavior among this population. We observed no significant differences in oxidative stress under the three levels of AA exposure (p > .05). It suggests a health concern for university students in Northwest China that should get society's attention.
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spelling pubmed-99221272023-02-13 Dietary exposure to acrylamide of university students in Ningxia of Northwest China and the effect on their neurobehavioral performance and oxidative stress in serum Gao, Qinghan Xue, Yanzhong Yuan, Xiao Gao, Hua Wu, Chunsen Food Sci Nutr Original Articles This study aims to investigate dietary exposure to acrylamide (AA) and also make an assessment of its effect on the neurobehavioral performance and oxidative stress in the serum of university students in Ningxia. The place primarily consists of arid, dry desert, and wheat‐based foods are the staple food there. A total of 803 university students in Ningxia participated in this cross‐sectional study. Diet intake of AA was estimated with FFQ. The AA risk was calculated as margin of exposure (MOE) values. NCTB questionnaires were used to assess neurobehavioral performance. The serum oxidative stress levels of the university students were measured as GSH, MDA, and SOD. The mean for AA exposure of university students was 0.515 μg kg(−1) bw day(−1). The highest contributor was traditional Chinese grain products, representing 34.71% of the total daily AA intake. Followed were deep‐fried potato products, traditional Western grain products, soft drinks, and nuts, which accounted for 23.87%, 16.59%, 11.15%, and 11%, respectively. The median AA exposure were 480 (BMDL(10) = 0.18 mg kg(−1) bw day(−1)) and 827 (BMDL(10) = 0.31 mg kg(−1) bw day(−1)), respectively. The results indicated that diet AA may have an effect on the emotional status and neurobehavior among this population. We observed no significant differences in oxidative stress under the three levels of AA exposure (p > .05). It suggests a health concern for university students in Northwest China that should get society's attention. John Wiley and Sons Inc. 2022-10-17 /pmc/articles/PMC9922127/ /pubmed/36789069 http://dx.doi.org/10.1002/fsn3.3101 Text en © 2022 The Authors. Food Science & Nutrition published by Wiley Periodicals LLC. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Gao, Qinghan
Xue, Yanzhong
Yuan, Xiao
Gao, Hua
Wu, Chunsen
Dietary exposure to acrylamide of university students in Ningxia of Northwest China and the effect on their neurobehavioral performance and oxidative stress in serum
title Dietary exposure to acrylamide of university students in Ningxia of Northwest China and the effect on their neurobehavioral performance and oxidative stress in serum
title_full Dietary exposure to acrylamide of university students in Ningxia of Northwest China and the effect on their neurobehavioral performance and oxidative stress in serum
title_fullStr Dietary exposure to acrylamide of university students in Ningxia of Northwest China and the effect on their neurobehavioral performance and oxidative stress in serum
title_full_unstemmed Dietary exposure to acrylamide of university students in Ningxia of Northwest China and the effect on their neurobehavioral performance and oxidative stress in serum
title_short Dietary exposure to acrylamide of university students in Ningxia of Northwest China and the effect on their neurobehavioral performance and oxidative stress in serum
title_sort dietary exposure to acrylamide of university students in ningxia of northwest china and the effect on their neurobehavioral performance and oxidative stress in serum
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9922127/
https://www.ncbi.nlm.nih.gov/pubmed/36789069
http://dx.doi.org/10.1002/fsn3.3101
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