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OAGB with shortened excluded ileal loop as an effective treatment for type 2 diabetes mellitus in the cases of Caucasian men and women with obesity of the first degree (BMI 30–35 kg/m(2))
INTRODUCTION: The aim of the study is to assess the effect of shortening the excluded loop of the small intestine to 150 cm on the effectiveness of one anastomosis gastric bypass (OAGB) in remission of type 2 diabetes with I(o) obesity. MATERIAL AND METHODS: The study included 25 patients with a bod...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9922227/ https://www.ncbi.nlm.nih.gov/pubmed/36773074 http://dx.doi.org/10.1007/s00423-023-02785-9 |
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author | Jaworski, Paweł Binda, Artur Barski, Krzysztof Wawiernia, Karolina Kudlicka, Emilia Wąsowski, Michał Jankowski, Piotr Tarnowski, Wiesław |
author_facet | Jaworski, Paweł Binda, Artur Barski, Krzysztof Wawiernia, Karolina Kudlicka, Emilia Wąsowski, Michał Jankowski, Piotr Tarnowski, Wiesław |
author_sort | Jaworski, Paweł |
collection | PubMed |
description | INTRODUCTION: The aim of the study is to assess the effect of shortening the excluded loop of the small intestine to 150 cm on the effectiveness of one anastomosis gastric bypass (OAGB) in remission of type 2 diabetes with I(o) obesity. MATERIAL AND METHODS: The study included 25 patients with a body mass index (BMI) 30–35 kg/m(2), with a diagnosis of diabetes mellitus type 2 (T2DM), and undergoing OAGB with excluded 150 cm of the small intestine. RESULTS: There were no deaths in the study group, bleeding during the postoperative period requiring reoperation, anastomotic leakage/leakage throught mechanical stitching. The mean a glycated haemoglobin (HbA1C) level 12 months after surgery was 6.16 ± 0.96%, corresponding to a 2.29 ± 3.3% decrease. In more than 85% of the patients taking insulin before surgery, the insulin was discontinued in the postoperative period. Additionally, the level of glycaemia was assessed in patients on the day of surgery (163 ± 58 mg/dl) and on the day of discharge from the hospital (4.7 ± 1.3 days)—it was lower by over 18% (133 ± 39.2 mg). Over the period of 12 months following OAGB, there was a reduction in the mean BMI value from 33.5 ± 2 to 25.5 ± 2.5 kg/m(2) and improvement in lipid parameters and mean values of blood pressure. CONCLUSION: OAGB with excluded 150 cm of the small intestine has beneficial effect on the remission of T2DM in patients with a BMI of 30–35kg/m(2) and is associated with an acceptable level of complications. The achieved weight loss after surgery is satisfactory. |
format | Online Article Text |
id | pubmed-9922227 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-99222272023-02-13 OAGB with shortened excluded ileal loop as an effective treatment for type 2 diabetes mellitus in the cases of Caucasian men and women with obesity of the first degree (BMI 30–35 kg/m(2)) Jaworski, Paweł Binda, Artur Barski, Krzysztof Wawiernia, Karolina Kudlicka, Emilia Wąsowski, Michał Jankowski, Piotr Tarnowski, Wiesław Langenbecks Arch Surg Research INTRODUCTION: The aim of the study is to assess the effect of shortening the excluded loop of the small intestine to 150 cm on the effectiveness of one anastomosis gastric bypass (OAGB) in remission of type 2 diabetes with I(o) obesity. MATERIAL AND METHODS: The study included 25 patients with a body mass index (BMI) 30–35 kg/m(2), with a diagnosis of diabetes mellitus type 2 (T2DM), and undergoing OAGB with excluded 150 cm of the small intestine. RESULTS: There were no deaths in the study group, bleeding during the postoperative period requiring reoperation, anastomotic leakage/leakage throught mechanical stitching. The mean a glycated haemoglobin (HbA1C) level 12 months after surgery was 6.16 ± 0.96%, corresponding to a 2.29 ± 3.3% decrease. In more than 85% of the patients taking insulin before surgery, the insulin was discontinued in the postoperative period. Additionally, the level of glycaemia was assessed in patients on the day of surgery (163 ± 58 mg/dl) and on the day of discharge from the hospital (4.7 ± 1.3 days)—it was lower by over 18% (133 ± 39.2 mg). Over the period of 12 months following OAGB, there was a reduction in the mean BMI value from 33.5 ± 2 to 25.5 ± 2.5 kg/m(2) and improvement in lipid parameters and mean values of blood pressure. CONCLUSION: OAGB with excluded 150 cm of the small intestine has beneficial effect on the remission of T2DM in patients with a BMI of 30–35kg/m(2) and is associated with an acceptable level of complications. The achieved weight loss after surgery is satisfactory. Springer Berlin Heidelberg 2023-02-11 2023 /pmc/articles/PMC9922227/ /pubmed/36773074 http://dx.doi.org/10.1007/s00423-023-02785-9 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/ Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Research Jaworski, Paweł Binda, Artur Barski, Krzysztof Wawiernia, Karolina Kudlicka, Emilia Wąsowski, Michał Jankowski, Piotr Tarnowski, Wiesław OAGB with shortened excluded ileal loop as an effective treatment for type 2 diabetes mellitus in the cases of Caucasian men and women with obesity of the first degree (BMI 30–35 kg/m(2)) |
title | OAGB with shortened excluded ileal loop as an effective treatment for type 2 diabetes mellitus in the cases of Caucasian men and women with obesity of the first degree (BMI 30–35 kg/m(2)) |
title_full | OAGB with shortened excluded ileal loop as an effective treatment for type 2 diabetes mellitus in the cases of Caucasian men and women with obesity of the first degree (BMI 30–35 kg/m(2)) |
title_fullStr | OAGB with shortened excluded ileal loop as an effective treatment for type 2 diabetes mellitus in the cases of Caucasian men and women with obesity of the first degree (BMI 30–35 kg/m(2)) |
title_full_unstemmed | OAGB with shortened excluded ileal loop as an effective treatment for type 2 diabetes mellitus in the cases of Caucasian men and women with obesity of the first degree (BMI 30–35 kg/m(2)) |
title_short | OAGB with shortened excluded ileal loop as an effective treatment for type 2 diabetes mellitus in the cases of Caucasian men and women with obesity of the first degree (BMI 30–35 kg/m(2)) |
title_sort | oagb with shortened excluded ileal loop as an effective treatment for type 2 diabetes mellitus in the cases of caucasian men and women with obesity of the first degree (bmi 30–35 kg/m(2)) |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9922227/ https://www.ncbi.nlm.nih.gov/pubmed/36773074 http://dx.doi.org/10.1007/s00423-023-02785-9 |
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