Cargando…

GPR137 Inhibits Cell Proliferation and Promotes Neuronal Differentiation in the Neuro2a Cells

The orphan receptor, G protein-coupled receptor 137 (GPR137), is an integral membrane protein involved in several types of cancer. GPR137 is expressed ubiquitously, including in the central nervous system (CNS). We established a GPR137 knockout (KO) neuro2A cell line to analyze GPR137 function in ne...

Descripción completa

Detalles Bibliográficos
Autores principales:	Iwasa, Kensuke, Yamagishi, Anzu, Yamamoto, Shinji, Haruta, Chikara, Maruyama, Kei, Yoshikawa, Keisuke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2022
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9922245/ https://www.ncbi.nlm.nih.gov/pubmed/36436172 http://dx.doi.org/10.1007/s11064-022-03833-4

Ejemplares similares

Long term administration of loquat leaves and their major component, ursolic acid, attenuated endogenous amyloid-β burden and memory impairment
por: Iwasa, Kensuke, et al.
Publicado: (2023)

A peripheral lipid sensor GPR120 remotely contributes to suppression of PGD(2)-microglia-provoked neuroinflammation and neurodegeneration in the mouse hippocampus
por: Iwasa, Kensuke, et al.
Publicado: (2021)

Correction to: Protective and therapeutic role of 2-carbacyclic phosphatidic acid in demyelinating disease
por: Yamamoto, Shinji, et al.
Publicado: (2018)

Protective and therapeutic role of 2-carba-cyclic phosphatidic acid in demyelinating disease
por: Yamamoto, Shinji, et al.
Publicado: (2017)

The ESRP1-GPR137 axis contributes to intestinal pathogenesis
por: Mager, Lukas Franz, et al.
Publicado: (2017)

Dietary oleic acid contributes to the regulation of food intake through the synthesis of intestinal oleoylethanolamide
por: Igarashi, Miki, et al.
Publicado: (2023)

GPR137 is a promising novel bio-marker for the prognosis of bladder cancer patients
por: Lu, Jianlei, et al.
Publicado: (2019)

Glio‐ and neuro‐protection by prosaposin is mediated by orphan G‐protein coupled receptors GPR37L1 and GPR37
por: Liu, Beihui, et al.
Publicado: (2018)

The lysosomal GPCR-like protein GPR137B regulates Rag and mTORC1 localization and activity
por: Gan, Lin, et al.
Publicado: (2019)

Niacin Ameliorates Neuro-Inflammation in Parkinson’s Disease via GPR109A
por: Giri, Banabihari, et al.
Publicado: (2019)

Datasets of microarray analysis to identify Gpr137b-dependent interleukin-4-responsive genes in the mouse macrophage cell line RAW264
por: Islam, Zohirul, et al.
Publicado: (2019)

miR-134-3p driven by anisomycin impairs ovarian cancer stem cell activity through inhibiting GPR137 expression
por: Ling, Lele, et al.
Publicado: (2023)

CircGPR137B/miR-4739/FTO feedback loop suppresses tumorigenesis and metastasis of hepatocellular carcinoma
por: Liu, Lianyong, et al.
Publicado: (2022)

GPR171 expression enhances proliferation and metastasis of lung cancer cells
por: Dho, So Hee, et al.
Publicado: (2016)

Regulatory T Cells Inhibit T Cell Activity by Downregulating CD137 Ligand via CD137 Trogocytosis
por: Luu, Khang, et al.
Publicado: (2021)

2-Carba-lysophosphatidic acid is a novel β-lysophosphatidic acid analogue with high potential for lysophosphatidic acid receptor activation and autotaxin inhibition
por: Fukasawa, Keiko, et al.
Publicado: (2021)

Inhibition of Proliferation and Induction of Apoptosis in Multiple Myeloma Cell Lines by CD137 Ligand Signaling
por: Gullo, Charles, et al.
Publicado: (2010)

Involvement of GPR17 in Neuronal Fibre Outgrowth
por: Braune, Max, et al.
Publicado: (2021)

miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells
por: Silber, Joachim, et al.
Publicado: (2008)

CD137-CD137 Ligand Interactions in Inflammation
por: Kwon, Byungsuk
Publicado: (2009)

Characterization of Four Orphan Receptors (GPR3, GPR6, GPR12 and GPR12L) in Chickens and Ducks and Regulation of GPR12 Expression in Ovarian Granulosa Cells by Progesterone
por: Li, Zejiao, et al.
Publicado: (2021)

Neuro-rejuvenation for neuronal function
por: Liu, Yuan, et al.
Publicado: (2016)

TCR-independent CD137 (4–1BB) signaling promotes CD8(+)-exhausted T cell proliferation and terminal differentiation
por: Pichler, Andrea C., et al.
Publicado: (2023)

MicroRNA-137 Upregulation Increases Bladder Cancer Cell Proliferation and Invasion by Targeting PAQR3
por: Xiu, Youcheng, et al.
Publicado: (2014)

MicroRNA-137 suppresses the proliferation, migration and invasion of cholangiocarcinoma cells by targeting WNT2B
por: Chen, Tengxiang, et al.
Publicado: (2020)

CD137(+) T-Cells: Protagonists of the Immunotherapy Revolution
por: Ugolini, Alessio, et al.
Publicado: (2021)

Glycine Effect on the Expression Profile of Orphan Receptors GPR21, GPR26, GPR39, GPR82 and GPR6 in a Model of Inflammation in 3T3-L1 Cells
por: Gutiérrez-Rojas, Rocío Alejandra, et al.
Publicado: (2022)

Genomic Analyses Reveal Broad Impact of miR-137 on Genes Associated with Malignant Transformation and Neuronal Differentiation in Glioblastoma Cells
por: Tamim, Saleh, et al.
Publicado: (2014)

miR-153-3p suppresses the differentiation and proliferation of neural stem cells via targeting GPR55
por: Dong, Xiaolin, et al.
Publicado: (2023)

The Mechanisms of GPR55 Receptor Functional Selectivity during Apoptosis and Proliferation Regulation in Cancer Cells
por: Akimov, Mikhail G., et al.
Publicado: (2023)

Down regulation of G protein-coupled receptor 137 expression inhibits proliferation and promotes apoptosis in leukemia cells
por: Men, Li-Jie, et al.
Publicado: (2018)

Retraction: MicroRNA-137 Upregulation Increases Bladder Cancer Cell Proliferation and Invasion by Targeting PAQR3
Publicado: (2022)

G Protein-Coupled Receptor 87 (GPR87) Promotes Cell Proliferation in Human Bladder Cancer Cells
por: Zhang, Xia, et al.
Publicado: (2015)

Curcumin alleviates LPS-induced inflammation and oxidative stress in mouse microglial BV2 cells by targeting miR-137-3p/NeuroD1
por: Gao, Feng, et al.
Publicado: (2019)

Hypoxia-induced soluble CD137 in malignant cells blocks CD137L-costimulation as an immune escape mechanism
por: Labiano, Sara, et al.
Publicado: (2014)

Increased Soluble CD137 Levels and CD4+ T‐Cell‐Associated Expression of CD137 in Acute Atherothrombotic Stroke
por: He, Yang, et al.
Publicado: (2018)

CD137 expression in cancer cells: regulation and significance
por: Glorieux, Christophe, et al.
Publicado: (2019)

Contributions of Costimulatory Molecule CD137 in Endothelial Cells
por: Yuan, Wei, et al.
Publicado: (2021)

Pax3 inhibits Neuro‐2a cells proliferation and neurite outgrowth
por: Huo, Bingqing, et al.
Publicado: (2020)

CircNEIL3 promotes cervical cancer cell proliferation by adsorbing miR-137 and upregulating KLF12
por: Chen, Yuan, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_gj17n2rtc984eq1n5tgn8j53r3