T cell-independent eradication of experimental glioma by intravenous TLR7/8-agonist-loaded nanoparticles

Glioblastoma, the most common and aggressive primary brain tumor type, is considered an immunologically “cold” tumor with sparse infiltration by adaptive immune cells. Immunosuppressive tumor-associated myeloid cells are drivers of tumor progression. Therefore, targeting and reprogramming intratumor...

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Detalles Bibliográficos
Autores principales: Turco, Verena, Pfleiderer, Kira, Hunger, Jessica, Horvat, Natalie K., Karimian-Jazi, Kianush, Schregel, Katharina, Fischer, Manuel, Brugnara, Gianluca, Jähne, Kristine, Sturm, Volker, Streibel, Yannik, Nguyen, Duy, Altamura, Sandro, Agardy, Dennis A., Soni, Shreya S., Alsasa, Abdulrahman, Bunse, Theresa, Schlesner, Matthias, Muckenthaler, Martina U., Weissleder, Ralph, Wick, Wolfgang, Heiland, Sabine, Vollmuth, Philipp, Bendszus, Martin, Rodell, Christopher B., Breckwoldt, Michael O., Platten, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9922247/
https://www.ncbi.nlm.nih.gov/pubmed/36774352
http://dx.doi.org/10.1038/s41467-023-36321-6

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