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Methylphenidate-Induced Menorrhagia in Twin Girls
Objective: Methylphenidate, a psychostimulant agent, is used in first-line psychopharmacological treatment in children and adolescents with attention-deficit/hyperactivity disorder. Common side effects associated with methylphenidate use in children and adolescents are insomnia, anorexia, headache,...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Psychiatry & Psychology Research Center, Tehran University of Medical Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9922357/ https://www.ncbi.nlm.nih.gov/pubmed/36817810 http://dx.doi.org/10.18502/ijps.v17i4.10698 |
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author | Özdağ, Veysel Koyuncu, Oğuzhan Özdemir, Yahya Esad Tanir, Yaşar |
author_facet | Özdağ, Veysel Koyuncu, Oğuzhan Özdemir, Yahya Esad Tanir, Yaşar |
author_sort | Özdağ, Veysel |
collection | PubMed |
description | Objective: Methylphenidate, a psychostimulant agent, is used in first-line psychopharmacological treatment in children and adolescents with attention-deficit/hyperactivity disorder. Common side effects associated with methylphenidate use in children and adolescents are insomnia, anorexia, headache, and nausea. Thrombocytopenia, nasal bleeding and menstrual bleeding disorders are very rarely reported during methylphenidate use. One of the least expected side effects during methylphenidate usage is menorrhagia. Method : In this article, we report methylphenidate monotherapy-induced menorrhagia in two adolescent identical twins. To our knowledge, this is the first report of menorrhagia associated with methylphenidate use in children and adolescents. Results: In both cases, menorrhagia has started after methylphenidate monotherapy and stopped after discontinuation. Other possible etiologies have excluded with clinical and laboratory evaluations. Naranjo Adverse Drug Reaction Probability Score was found 7, indicates probable side effect. Conclusion: Menorrhagia is a rare adverse effect of methylphenidate use and clinicians should be aware of this phenomenon. |
format | Online Article Text |
id | pubmed-9922357 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Psychiatry & Psychology Research Center, Tehran University of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-99223572023-02-16 Methylphenidate-Induced Menorrhagia in Twin Girls Özdağ, Veysel Koyuncu, Oğuzhan Özdemir, Yahya Esad Tanir, Yaşar Iran J Psychiatry Case Report Objective: Methylphenidate, a psychostimulant agent, is used in first-line psychopharmacological treatment in children and adolescents with attention-deficit/hyperactivity disorder. Common side effects associated with methylphenidate use in children and adolescents are insomnia, anorexia, headache, and nausea. Thrombocytopenia, nasal bleeding and menstrual bleeding disorders are very rarely reported during methylphenidate use. One of the least expected side effects during methylphenidate usage is menorrhagia. Method : In this article, we report methylphenidate monotherapy-induced menorrhagia in two adolescent identical twins. To our knowledge, this is the first report of menorrhagia associated with methylphenidate use in children and adolescents. Results: In both cases, menorrhagia has started after methylphenidate monotherapy and stopped after discontinuation. Other possible etiologies have excluded with clinical and laboratory evaluations. Naranjo Adverse Drug Reaction Probability Score was found 7, indicates probable side effect. Conclusion: Menorrhagia is a rare adverse effect of methylphenidate use and clinicians should be aware of this phenomenon. Psychiatry & Psychology Research Center, Tehran University of Medical Sciences 2022-10 /pmc/articles/PMC9922357/ /pubmed/36817810 http://dx.doi.org/10.18502/ijps.v17i4.10698 Text en Copyright © 2022 Tehran University of Medical Sciences. Published by Tehran University of Medical Sciences. https://creativecommons.org/licenses/by-nc/4.0/This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International license (https://creativecommons.org/licenses/by-nc/4.0/). Non-commercial uses of the work are permitted, provided the original work is properly cited. |
spellingShingle | Case Report Özdağ, Veysel Koyuncu, Oğuzhan Özdemir, Yahya Esad Tanir, Yaşar Methylphenidate-Induced Menorrhagia in Twin Girls |
title | Methylphenidate-Induced Menorrhagia in Twin Girls |
title_full | Methylphenidate-Induced Menorrhagia in Twin Girls |
title_fullStr | Methylphenidate-Induced Menorrhagia in Twin Girls |
title_full_unstemmed | Methylphenidate-Induced Menorrhagia in Twin Girls |
title_short | Methylphenidate-Induced Menorrhagia in Twin Girls |
title_sort | methylphenidate-induced menorrhagia in twin girls |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9922357/ https://www.ncbi.nlm.nih.gov/pubmed/36817810 http://dx.doi.org/10.18502/ijps.v17i4.10698 |
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