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11β-Hydroxysteroid dehydrogenase type 1 amplifies inflammation in LPS-induced THP-1 cells

OBJECTIVE(S): The role of glucocorticoids as anti-inflammatory and immune-stimulatory drugs has been widely reported. However, the role of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1), which catalyzes the conversion of inactive cortisone into active cortisol, in inflammation remains unclear. T...

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Detalles Bibliográficos
Autores principales:	Luo, Lingli, Zhu, Dongmei, Zhang, Zheng, Zeng, Hanjie, Huang, Min, Zhou, Suming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Mashhad University of Medical Sciences 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9922366/ https://www.ncbi.nlm.nih.gov/pubmed/36865036 http://dx.doi.org/10.22038/IJBMS.2023.67927.14852

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