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Protective effects of baicalin against L-glutamate-induced oxidative damage in HT-22 cells by inhibiting NLRP3 inflammasome activation via Nrf2/HO-1 signaling

OBJECTIVE(S): To explore the ability and underlying molecular mechanisms involved in the protective effects of Baicalin (BA) against L-Glutamate-induced mouse hippocampal neuron cell line HT-22. MATERIALS AND METHODS: The cell injury model of HT-22 cells was induced by L-glutamate, and cell viabilit...

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Detalles Bibliográficos
Autores principales: Li, Junyuan, Wang, Gang, Zhang, Yehao, Fan, Xiaodi, Yao, Mingjiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9922368/
https://www.ncbi.nlm.nih.gov/pubmed/36865047
http://dx.doi.org/10.22038/IJBMS.2023.64318.14149