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Triglyceride glucose index and poor sleep patterns in non-diabetic adults: Evidence from NHANES 2005–2016

INTRODUCTION: Sleep disorders are commonly encountered in modern populations. This cross-sectional study aimed to investigate the associations between triglyceride glucose (TyG) index and poor sleep patterns in non-diabetic adults. METHODS: Data of non-diabetic adults aged 20–70 years were extracted...

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Autores principales: Liu, Chi-Feng, Chien, Li-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9922746/
https://www.ncbi.nlm.nih.gov/pubmed/36793924
http://dx.doi.org/10.3389/fnut.2023.1051667
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author Liu, Chi-Feng
Chien, Li-Wei
author_facet Liu, Chi-Feng
Chien, Li-Wei
author_sort Liu, Chi-Feng
collection PubMed
description INTRODUCTION: Sleep disorders are commonly encountered in modern populations. This cross-sectional study aimed to investigate the associations between triglyceride glucose (TyG) index and poor sleep patterns in non-diabetic adults. METHODS: Data of non-diabetic adults aged 20–70 years were extracted from the US National Health and Nutrition Examination Survey database 2005–2016. Pregnant women, individuals with diabetes and cancer history, and individuals lacking complete data on sleep patterns or parameters for calculating TyG index were excluded. Poor sleep pattern was defined as having two or more following conditions: (1) abnormal sleep duration, defined as less than 7 h or longer than 9 h; (2) self-reported trouble sleeping; and (3) physician-confirmed sleep disorders. Associations between poor sleep patterns, TyG index, and an additional index incorporating body mass index (BMI), TyGBMI, and other study variables were determined by univariable and multivariable logistic regression analysis. RESULTS: Among 9,390 included participants, 1,422 had poor sleep patterns and 7,968 did not. The individuals with poor sleep patterns had a higher mean TyG index, were older, had higher BMI, and had higher proportions of hypertension and history of CVD than those without poor sleep pattern (all p < 0.001). Multivariable analysis showed no significant association between poor sleep pattern and TyG index. However, among the components of poor sleep pattern, TyG index in the highest quartile (Q4) was significantly associated with trouble sleeping [adjusted OR (aOR): 1.46, 95%CI: 1.04–2.03) as compared with the lowest TyG quartile (Q1). In addition, TyG-BMI in Q4 was indepently associated with increased likelihood for poor sleep patterns (aOR: 2.18, 95%CI: 1.61–2.95), trouble sleeping (aOR: 1.76, 95%CI: 1.30–2.39), abnormal sleep duration (aOR: 1.41, 95%CI: 1.12–1.78), and sleep disorders (aOR: 3.11, 95%CI: 2.08–4.64) as compared to Q1. DISCUSSION: Among US adults without diabetes, elevated TyG index is correlated with self-reported trouble sleeping, independent of BMI. Future studies should build upon this preliminary work and examine these associations longitudinally and through treatment trials.
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spelling pubmed-99227462023-02-14 Triglyceride glucose index and poor sleep patterns in non-diabetic adults: Evidence from NHANES 2005–2016 Liu, Chi-Feng Chien, Li-Wei Front Nutr Nutrition INTRODUCTION: Sleep disorders are commonly encountered in modern populations. This cross-sectional study aimed to investigate the associations between triglyceride glucose (TyG) index and poor sleep patterns in non-diabetic adults. METHODS: Data of non-diabetic adults aged 20–70 years were extracted from the US National Health and Nutrition Examination Survey database 2005–2016. Pregnant women, individuals with diabetes and cancer history, and individuals lacking complete data on sleep patterns or parameters for calculating TyG index were excluded. Poor sleep pattern was defined as having two or more following conditions: (1) abnormal sleep duration, defined as less than 7 h or longer than 9 h; (2) self-reported trouble sleeping; and (3) physician-confirmed sleep disorders. Associations between poor sleep patterns, TyG index, and an additional index incorporating body mass index (BMI), TyGBMI, and other study variables were determined by univariable and multivariable logistic regression analysis. RESULTS: Among 9,390 included participants, 1,422 had poor sleep patterns and 7,968 did not. The individuals with poor sleep patterns had a higher mean TyG index, were older, had higher BMI, and had higher proportions of hypertension and history of CVD than those without poor sleep pattern (all p < 0.001). Multivariable analysis showed no significant association between poor sleep pattern and TyG index. However, among the components of poor sleep pattern, TyG index in the highest quartile (Q4) was significantly associated with trouble sleeping [adjusted OR (aOR): 1.46, 95%CI: 1.04–2.03) as compared with the lowest TyG quartile (Q1). In addition, TyG-BMI in Q4 was indepently associated with increased likelihood for poor sleep patterns (aOR: 2.18, 95%CI: 1.61–2.95), trouble sleeping (aOR: 1.76, 95%CI: 1.30–2.39), abnormal sleep duration (aOR: 1.41, 95%CI: 1.12–1.78), and sleep disorders (aOR: 3.11, 95%CI: 2.08–4.64) as compared to Q1. DISCUSSION: Among US adults without diabetes, elevated TyG index is correlated with self-reported trouble sleeping, independent of BMI. Future studies should build upon this preliminary work and examine these associations longitudinally and through treatment trials. Frontiers Media S.A. 2023-01-30 /pmc/articles/PMC9922746/ /pubmed/36793924 http://dx.doi.org/10.3389/fnut.2023.1051667 Text en Copyright © 2023 Liu and Chien. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Nutrition
Liu, Chi-Feng
Chien, Li-Wei
Triglyceride glucose index and poor sleep patterns in non-diabetic adults: Evidence from NHANES 2005–2016
title Triglyceride glucose index and poor sleep patterns in non-diabetic adults: Evidence from NHANES 2005–2016
title_full Triglyceride glucose index and poor sleep patterns in non-diabetic adults: Evidence from NHANES 2005–2016
title_fullStr Triglyceride glucose index and poor sleep patterns in non-diabetic adults: Evidence from NHANES 2005–2016
title_full_unstemmed Triglyceride glucose index and poor sleep patterns in non-diabetic adults: Evidence from NHANES 2005–2016
title_short Triglyceride glucose index and poor sleep patterns in non-diabetic adults: Evidence from NHANES 2005–2016
title_sort triglyceride glucose index and poor sleep patterns in non-diabetic adults: evidence from nhanes 2005–2016
topic Nutrition
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9922746/
https://www.ncbi.nlm.nih.gov/pubmed/36793924
http://dx.doi.org/10.3389/fnut.2023.1051667
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