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Acquired reactive perforating collagenosis combined with MRSA: A case report

Acquired reactive perforating collagenosis (ARPC) is a rare chronic skin disease associated with various internal diseases, particularly diabetes and chronic renal failure. The present study describes the case of a patient with ARPC combined with methicillin-resistant Staphylococcus aureus (MRSA), i...

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Autores principales: Huang, Fuqian, Ren, Weiqi, Wang, Miaomiao, Li, Xiufang, Pan, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9922796/
https://www.ncbi.nlm.nih.gov/pubmed/36793622
http://dx.doi.org/10.3892/mi.2023.69
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author Huang, Fuqian
Ren, Weiqi
Wang, Miaomiao
Li, Xiufang
Pan, Min
author_facet Huang, Fuqian
Ren, Weiqi
Wang, Miaomiao
Li, Xiufang
Pan, Min
author_sort Huang, Fuqian
collection PubMed
description Acquired reactive perforating collagenosis (ARPC) is a rare chronic skin disease associated with various internal diseases, particularly diabetes and chronic renal failure. The present study describes the case of a patient with ARPC combined with methicillin-resistant Staphylococcus aureus (MRSA), in an aim to broaden the current understanding of ARPC. A 75-year-old female presented with a 5-year history of pruritus and ulcerative eruptions on the trunk of her body, which became more severe within 1 year. A cutaneous examination revealed a diffuse distribution of erythema and papules, and nodules of various sizes, some of which sagged at the center and had a dark brown crust. A histopathological analysis revealed typical perforations of the collagen fibers. The patient was initially treated with topical corticosteroids and oral antihistamines for skin lesions and pruritus. Medications for glucose control were also administered. Upon the second admission, a combination of antibiotics and acitretin was added. The keratin plug shrank, and the pruritus was relieved. To date, to the best of our knowledge, this is the first reported case of concurrent ARPC and MRSA.
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spelling pubmed-99227962023-02-14 Acquired reactive perforating collagenosis combined with MRSA: A case report Huang, Fuqian Ren, Weiqi Wang, Miaomiao Li, Xiufang Pan, Min Med Int (Lond) Case Report Acquired reactive perforating collagenosis (ARPC) is a rare chronic skin disease associated with various internal diseases, particularly diabetes and chronic renal failure. The present study describes the case of a patient with ARPC combined with methicillin-resistant Staphylococcus aureus (MRSA), in an aim to broaden the current understanding of ARPC. A 75-year-old female presented with a 5-year history of pruritus and ulcerative eruptions on the trunk of her body, which became more severe within 1 year. A cutaneous examination revealed a diffuse distribution of erythema and papules, and nodules of various sizes, some of which sagged at the center and had a dark brown crust. A histopathological analysis revealed typical perforations of the collagen fibers. The patient was initially treated with topical corticosteroids and oral antihistamines for skin lesions and pruritus. Medications for glucose control were also administered. Upon the second admission, a combination of antibiotics and acitretin was added. The keratin plug shrank, and the pruritus was relieved. To date, to the best of our knowledge, this is the first reported case of concurrent ARPC and MRSA. D.A. Spandidos 2023-01-26 /pmc/articles/PMC9922796/ /pubmed/36793622 http://dx.doi.org/10.3892/mi.2023.69 Text en Copyright: © Huang et al. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (https://creativecommons.org/licenses/by-nc-nd/4.0/) , which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
spellingShingle Case Report
Huang, Fuqian
Ren, Weiqi
Wang, Miaomiao
Li, Xiufang
Pan, Min
Acquired reactive perforating collagenosis combined with MRSA: A case report
title Acquired reactive perforating collagenosis combined with MRSA: A case report
title_full Acquired reactive perforating collagenosis combined with MRSA: A case report
title_fullStr Acquired reactive perforating collagenosis combined with MRSA: A case report
title_full_unstemmed Acquired reactive perforating collagenosis combined with MRSA: A case report
title_short Acquired reactive perforating collagenosis combined with MRSA: A case report
title_sort acquired reactive perforating collagenosis combined with mrsa: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9922796/
https://www.ncbi.nlm.nih.gov/pubmed/36793622
http://dx.doi.org/10.3892/mi.2023.69
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