Phosphorylation alters the mechanical stiffness of a model fragment of the dystrophin homologue utrophin

Duchenne muscular dystrophy is a lethal muscle wasting disease caused by the absence of the protein dystrophin. Utrophin is a dystrophin homologue currently under investigation as a protein replacement therapy for Duchenne muscular dystrophy. Dystrophin is hypothesized to function as a molecular sho...

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Detalles Bibliográficos
Autores principales: Ramirez, Maria Paz, Rajaganapathy, Sivaraman, Hagerty, Anthony R., Hua, Cailong, Baxter, Gloria C., Vavra, Joseph, Gordon, Wendy R., Muretta, Joseph M., Salapaka, Murti V., Ervasti, James M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9922815/
https://www.ncbi.nlm.nih.gov/pubmed/36587764
http://dx.doi.org/10.1016/j.jbc.2022.102847

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