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Innovative COVID-19 point-of-care diagnostics suitable for tuberculosis diagnosis: a scoping review protocol

INTRODUCTION: In 2014, the WHO published high-priority target product profiles (TPPs) for new tuberculosis (TB) diagnostics to align end-user needs with test targets and specifications; nevertheless, no TB test meets these targets to date. The COVID-19-driven momentum in the diagnostics world offers...

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Autores principales: Yerlikaya, Seda, Holtgrewe, Lydia Marie-Luise, Broger, Tobias, Isaacs, Chris, Nahid, Payam, Cattamanchi, Adithya, Denkinger, Claudia M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9922875/
https://www.ncbi.nlm.nih.gov/pubmed/36754560
http://dx.doi.org/10.1136/bmjopen-2022-065194
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author Yerlikaya, Seda
Holtgrewe, Lydia Marie-Luise
Broger, Tobias
Isaacs, Chris
Nahid, Payam
Cattamanchi, Adithya
Denkinger, Claudia M
author_facet Yerlikaya, Seda
Holtgrewe, Lydia Marie-Luise
Broger, Tobias
Isaacs, Chris
Nahid, Payam
Cattamanchi, Adithya
Denkinger, Claudia M
author_sort Yerlikaya, Seda
collection PubMed
description INTRODUCTION: In 2014, the WHO published high-priority target product profiles (TPPs) for new tuberculosis (TB) diagnostics to align end-user needs with test targets and specifications; nevertheless, no TB test meets these targets to date. The COVID-19-driven momentum in the diagnostics world offers an opportunity to address the long-standing lack of innovation in the field of TB diagnostics. This scoping review aims to summarise point-of-care (POC) molecular and antigen tests for COVID-19 diagnosis that, when applied to TB, potentially meet WHO TPPs. This summary of currently available innovative diagnostic tools will guide the development of novel TB diagnostics toward the WHO-set targets. METHODS AND ANALYSIS: We will follow the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension Scoping Reviews recommendations. MEDLINE (via PubMed), bioRxiv, MedRxiv and other publicly available in vitro diagnostic test databases were searched on 23 November 2022. POC antigen or molecular tests developed for SARS-CoV-2 detection that meet the eligibility criteria will be included in the review. Developer description, test description, operation characteristics, pricing information, performance and commercialisation status of diagnostic tests identified will be extracted using a predefined standardised data extraction form. Two reviewers will independently perform the screening and data extraction. A narrative synthesis of the final data will be provided. ETHICS AND DISSEMINATION: No ethical approval is required because individual patient data will not be included. The findings will be published in open-access scientific journals.
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spelling pubmed-99228752023-02-13 Innovative COVID-19 point-of-care diagnostics suitable for tuberculosis diagnosis: a scoping review protocol Yerlikaya, Seda Holtgrewe, Lydia Marie-Luise Broger, Tobias Isaacs, Chris Nahid, Payam Cattamanchi, Adithya Denkinger, Claudia M BMJ Open Infectious Diseases INTRODUCTION: In 2014, the WHO published high-priority target product profiles (TPPs) for new tuberculosis (TB) diagnostics to align end-user needs with test targets and specifications; nevertheless, no TB test meets these targets to date. The COVID-19-driven momentum in the diagnostics world offers an opportunity to address the long-standing lack of innovation in the field of TB diagnostics. This scoping review aims to summarise point-of-care (POC) molecular and antigen tests for COVID-19 diagnosis that, when applied to TB, potentially meet WHO TPPs. This summary of currently available innovative diagnostic tools will guide the development of novel TB diagnostics toward the WHO-set targets. METHODS AND ANALYSIS: We will follow the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension Scoping Reviews recommendations. MEDLINE (via PubMed), bioRxiv, MedRxiv and other publicly available in vitro diagnostic test databases were searched on 23 November 2022. POC antigen or molecular tests developed for SARS-CoV-2 detection that meet the eligibility criteria will be included in the review. Developer description, test description, operation characteristics, pricing information, performance and commercialisation status of diagnostic tests identified will be extracted using a predefined standardised data extraction form. Two reviewers will independently perform the screening and data extraction. A narrative synthesis of the final data will be provided. ETHICS AND DISSEMINATION: No ethical approval is required because individual patient data will not be included. The findings will be published in open-access scientific journals. BMJ Publishing Group 2023-02-08 /pmc/articles/PMC9922875/ /pubmed/36754560 http://dx.doi.org/10.1136/bmjopen-2022-065194 Text en © Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) .
spellingShingle Infectious Diseases
Yerlikaya, Seda
Holtgrewe, Lydia Marie-Luise
Broger, Tobias
Isaacs, Chris
Nahid, Payam
Cattamanchi, Adithya
Denkinger, Claudia M
Innovative COVID-19 point-of-care diagnostics suitable for tuberculosis diagnosis: a scoping review protocol
title Innovative COVID-19 point-of-care diagnostics suitable for tuberculosis diagnosis: a scoping review protocol
title_full Innovative COVID-19 point-of-care diagnostics suitable for tuberculosis diagnosis: a scoping review protocol
title_fullStr Innovative COVID-19 point-of-care diagnostics suitable for tuberculosis diagnosis: a scoping review protocol
title_full_unstemmed Innovative COVID-19 point-of-care diagnostics suitable for tuberculosis diagnosis: a scoping review protocol
title_short Innovative COVID-19 point-of-care diagnostics suitable for tuberculosis diagnosis: a scoping review protocol
title_sort innovative covid-19 point-of-care diagnostics suitable for tuberculosis diagnosis: a scoping review protocol
topic Infectious Diseases
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9922875/
https://www.ncbi.nlm.nih.gov/pubmed/36754560
http://dx.doi.org/10.1136/bmjopen-2022-065194
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