New protocol for kinetic assay seeding ability recovery “KASAR” from formalin-fixed paraffin-embedded tissues

The real-time quaking-induced conversion (RT-QuIC) alpha-synuclein (aSyn) protein kinetic seeding assay has been very useful for detecting pathological aggregates in various synucleinopathies including Parkinson’s disease (PD). This biomarker assay relies on fresh frozen tissue to effectively seed a...

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Detalles Bibliográficos
Autores principales: Hepker, Monica, Clabaugh, Griffin, Jin, Huajun, Kanthasamy, Anumantha G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9922999/
https://www.ncbi.nlm.nih.gov/pubmed/36793788
http://dx.doi.org/10.3389/fmolb.2023.1087982

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9922999/
https://www.ncbi.nlm.nih.gov/pubmed/36793788
http://dx.doi.org/10.3389/fmolb.2023.1087982

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