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Evaluation of the mutant selection window of danofloxacin against Actinobacillus pleuropneumoniae in an in vitro dynamic model

INTRODUCTION: The rapid emergence and widespread spread of multidrug-resistant bacteria is a serious threat to the health of humans and animals. The pharmacokinetic/pharmacodynamic (PK/PD) integration model based on mutant selection window (MSW) theory is an important method to optimize the dosage r...

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Detalles Bibliográficos
Autores principales: Zhang, Longfei, Wang, Hongjuan, Bai, Yilin, Wang, Lei, Bai, Yueyu, Hu, Jianhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9923107/
https://www.ncbi.nlm.nih.gov/pubmed/36793382
http://dx.doi.org/10.3389/fvets.2023.1107608