Novel method to quantify peptidylarginine deiminase activity shows distinct citrullination patterns in rheumatoid and juvenile idiopathic arthritis

INTRODUCTION: Peptidylarginine deiminases (PADs) mediate citrullination, an irreversible posttranslational modification that converts arginine to citrulline residues in proteins. Rheumatoid arthritis (RA) is characterized by unique autoantibodies that recognize citrullinated peptides, which are high...

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Detalles Bibliográficos
Autores principales: Yu, Karen, Dillemans, Luna, Gouwy, Mieke, Bessa, Helena, Metzemaekers, Mieke, Martens, Erik, Matthys, Patrick, Bossuyt, Xavier, Verschueren, Patrick, Wouters, Carine, De Somer, Lien, Proost, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9923157/
https://www.ncbi.nlm.nih.gov/pubmed/36793709
http://dx.doi.org/10.3389/fimmu.2023.1111465

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