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Spindle cell oncocytoma of the pituitary tumor: A rare case report and literature reviews

INTRODUCTION: Spindle cell oncocytoma (SCO) of the pituitary gland is increasingly established with improvements in histological and immunohistochemical examination. However, the diagnosis was often mistaken based on imaging studies and nonspecific clinical manifestations. PURPOSE: This case is pres...

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Autores principales: Chang, Chia Ning, Shen, Chiung Chyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9923168/
https://www.ncbi.nlm.nih.gov/pubmed/36793516
http://dx.doi.org/10.3389/fsurg.2022.1021680
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author Chang, Chia Ning
Shen, Chiung Chyi
author_facet Chang, Chia Ning
Shen, Chiung Chyi
author_sort Chang, Chia Ning
collection PubMed
description INTRODUCTION: Spindle cell oncocytoma (SCO) of the pituitary gland is increasingly established with improvements in histological and immunohistochemical examination. However, the diagnosis was often mistaken based on imaging studies and nonspecific clinical manifestations. PURPOSE: This case is presented to provide an overview of the characteristics of the rare tumor as well as to demonstrate the difficulties in diagnosis and current treatments. CLINICAL DISCUSSION: The pathogenesis of SCO remains unclear, and a possible origin was described. Further research is needed to optimize pre-operative diagnosis and surgical strategy. CONCLUSION: SCO should be considered when images indicate some features. Gross total resection (GTR) after surgery seems to have better long-term tumor control, and radiotherapy may help decrease tumor progression in patients with non-GTR. Regular follow-up is advised because of the higher recurrence rate.
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spelling pubmed-99231682023-02-14 Spindle cell oncocytoma of the pituitary tumor: A rare case report and literature reviews Chang, Chia Ning Shen, Chiung Chyi Front Surg Surgery INTRODUCTION: Spindle cell oncocytoma (SCO) of the pituitary gland is increasingly established with improvements in histological and immunohistochemical examination. However, the diagnosis was often mistaken based on imaging studies and nonspecific clinical manifestations. PURPOSE: This case is presented to provide an overview of the characteristics of the rare tumor as well as to demonstrate the difficulties in diagnosis and current treatments. CLINICAL DISCUSSION: The pathogenesis of SCO remains unclear, and a possible origin was described. Further research is needed to optimize pre-operative diagnosis and surgical strategy. CONCLUSION: SCO should be considered when images indicate some features. Gross total resection (GTR) after surgery seems to have better long-term tumor control, and radiotherapy may help decrease tumor progression in patients with non-GTR. Regular follow-up is advised because of the higher recurrence rate. Frontiers Media S.A. 2023-01-30 /pmc/articles/PMC9923168/ /pubmed/36793516 http://dx.doi.org/10.3389/fsurg.2022.1021680 Text en © 2023 Chang and Shen. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (https://creativecommons.org/licenses/by/4.0/) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Surgery
Chang, Chia Ning
Shen, Chiung Chyi
Spindle cell oncocytoma of the pituitary tumor: A rare case report and literature reviews
title Spindle cell oncocytoma of the pituitary tumor: A rare case report and literature reviews
title_full Spindle cell oncocytoma of the pituitary tumor: A rare case report and literature reviews
title_fullStr Spindle cell oncocytoma of the pituitary tumor: A rare case report and literature reviews
title_full_unstemmed Spindle cell oncocytoma of the pituitary tumor: A rare case report and literature reviews
title_short Spindle cell oncocytoma of the pituitary tumor: A rare case report and literature reviews
title_sort spindle cell oncocytoma of the pituitary tumor: a rare case report and literature reviews
topic Surgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9923168/
https://www.ncbi.nlm.nih.gov/pubmed/36793516
http://dx.doi.org/10.3389/fsurg.2022.1021680
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