Cargando…

Design of highly active substrates using molecular docking for microbial transglutaminase detection

The transglutaminase (TGase) family catalyzes a transamidation reaction between glutamine (Gln) and lysine (Lys) residues on protein substrates. Highly active substrates are important for cross-linking and modifying proteins of TGase. In the present work, high-activity substrates have been designed...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zou, Longhao, Geng, Xu, Li, Zhengqiang, Li, Tao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2023
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9923216/ https://www.ncbi.nlm.nih.gov/pubmed/36793302 http://dx.doi.org/10.1039/d2ra06467g

Ejemplares similares

Substrate specificity of microbial transglutaminase as revealed by three-dimensional docking simulation and mutagenesis
por: Tagami, Uno, et al.
Publicado: (2009)

Microbial transglutaminase nanoflowers as an alternative nanomedicine for breast cancer theranostics
por: Fatima, Syeda Warisul, et al.
Publicado: (2021)

Angular Phenozaxine Ethers as Potent Multi-microbial Targets Inhibitors: Design, Synthesis, and Molecular Docking Studies
por: Ezeokonkwo, Mercy A., et al.
Publicado: (2017)

Tag-free, specific conjugation of glycosylated IgG1 antibodies using microbial transglutaminase
por: Hadjabdelhafid-Parisien, Adem, et al.
Publicado: (2022)

Characterization of Gelatin Hydrogels Cross-Linked with Microbial Transglutaminase as Engineered Skeletal Muscle Substrates
por: Gupta, Divya, et al.
Publicado: (2021)

Tissue Transglutaminase but Not Microbial Transglutaminase Is Inhibited by Exogenous Oxidative Substances in Celiac Disease
por: Stricker, Sebastian, et al.
Publicado: (2022)

Structure-Based Design, Synthesis, Biological Evaluation, and Molecular Docking of Novel PDE10 Inhibitors With Antioxidant Activities
por: Li, Jinxuan, et al.
Publicado: (2018)

Bcr is a substrate for Transglutaminase 2 cross-linking activity
por: Yi, Sun-Ju, et al.
Publicado: (2011)

High-level expression of a recombinant active microbial transglutaminase in Escherichia coli
por: Salis, Barbara, et al.
Publicado: (2015)

Folic acid-sulfonamide conjugates as antibacterial agents: design, synthesis and molecular docking studies
por: Shahzad, Shabnam, et al.
Publicado: (2020)

Identification of promising anti-EBOV inhibitors: de novo drug design, molecular docking and molecular dynamics studies
por: Mohamed, Eslam A. R., et al.
Publicado: (2022)

Design of a glutamine substrate tag enabling protein labelling mediated by Bacillus subtilis transglutaminase
por: Oteng-Pabi, Samuel K., et al.
Publicado: (2018)

Design, synthesis, molecular docking and DFT studies on novel melatonin and isatin based azole derivatives
por: Saini, Keshav Kumar, et al.
Publicado: (2023)

Novel quercetin and apigenin-acetamide derivatives: design, synthesis, characterization, biological evaluation and molecular docking studies
por: Isika, Daniel, et al.
Publicado: (2020)

Design, synthesis, biological evaluation and molecular docking study of novel pyridoxine–triazoles as anti-Alzheimer's agents
por: Pal, Tiyas, et al.
Publicado: (2020)

Combined 3D-QSAR, molecular docking and dynamics simulations studies to model and design TTK inhibitors
por: Ashraf, Noureen, et al.
Publicado: (2022)

Covalent-Assembly Based Fluorescent Probes for Detection of hNQO1 and Imaging in Living Cells
por: Han, Jialing, et al.
Publicado: (2020)

Discovery of a microbial transglutaminase enabling highly site-specific labeling of proteins
por: Steffen, Wojtek, et al.
Publicado: (2017)

Preparation and characteristics of gelatin sponges crosslinked by microbial transglutaminase
por: Long, Haiyan, et al.
Publicado: (2017)

Design, synthetic approach, in silico molecular docking and antibacterial activity of quinazolin-2,4-dione hybrids bearing bioactive scaffolds
por: Abdelmonsef, Aboubakr H., et al.
Publicado: (2022)

Triarylethylene-indolin-2,3-dione molecular conjugates: design, synthesis, docking studies and anti-proliferation evaluation
por: Kumar, Sumit, et al.
Publicado: (2019)

Novel adamantyl clubbed iminothiazolidinones as promising elastase inhibitors: design, synthesis, molecular docking, ADMET and DFT studies
por: Ahmed, Atteeque, et al.
Publicado: (2022)

Enhancing glycan stability via site-selective fluorination: modulating substrate orientation by molecular design
por: Axer, Alexander, et al.
Publicado: (2020)

Detection of transglutaminase activity using click chemistry
por: van Geel, Remon, et al.
Publicado: (2011)

Isozyme-specific comprehensive characterization of transglutaminase-crosslinked substrates in kidney fibrosis
por: Tatsukawa, Hideki, et al.
Publicado: (2018)

Design of screen-printed potentiometric platform for sensitive determination of mirabegron in spiked human plasma; molecular docking and transducer optimization
por: Mouhamed, Aya A., et al.
Publicado: (2023)

A molecular approach to rationally constructing specific fluorogenic substrates for the detection of acetylcholinesterase activity in live cells, mice brains and tissues
por: Wu, Xiaofeng, et al.
Publicado: (2020)

Synthesis, bioactivity, and molecular docking of novel arylpiperazine derivatives as potential AR antagonists
por: Qi, Yueheng, et al.
Publicado: (2022)

Molecular Docking-Based Design and Development of a Highly Selective Probe Substrate for UDP-glucuronosyltransferase 1A10
por: Juvonen, Risto O., et al.
Publicado: (2018)

Microbial transglutaminase and its application in the food industry. A review
por: Kieliszek, Marek, et al.
Publicado: (2013)

Microbial Transglutaminase Is Immunogenic and Potentially Pathogenic in Pediatric Celiac Disease
por: Torsten, Matthias, et al.
Publicado: (2018)

Microbial transglutaminase should be considered as an environmental inducer of celiac disease
por: Lerner, Aaron, et al.
Publicado: (2019)

Site Selective Antibody-Oligonucleotide Conjugation via Microbial Transglutaminase
por: Huggins, Ian J., et al.
Publicado: (2019)

Molecular docking analysis and anti-hyperglycaemic activity of Synacinn™ in streptozotocin-induced rats
por: Ab Rahman, Nur Syukriah, et al.
Publicado: (2020)

Discovery of Novel α-Aminophosphonates with Hydrazone as Potential Antiviral Agents Combined With Active Fragment and Molecular Docking
por: Tian, Jia, et al.
Publicado: (2022)

Designing Uniformly Layered FeTiO(3) Assemblies Consisting of Fine Nanoparticles Enabling High-Performance Quasi-Solid-State Sodium-Ion Capacitors
por: Liu, Lei, et al.
Publicado: (2020)

Accurate binding of porous aluminum molecular ring catalysts with the substrate
por: Luo, Dan, et al.
Publicado: (2023)

Phenylalanyl tRNA synthetase (PheRS) substrate mimics: design, synthesis, molecular dynamics and antimicrobial evaluation
por: Noureldin, Nada A., et al.
Publicado: (2022)

Synthesis, Antimicrobial Activity, Structure-Activity Relationship, and Molecular Docking Studies of Indole Diketopiperazine Alkaloids
por: Jia, Bin, et al.
Publicado: (2019)

Autoantibody binding and unique enzyme-substrate intermediate conformation of human transglutaminase 3
por: Heggelund, Julie Elisabeth, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_4b2j0gpl3go3sfknvkb8ukg0h4