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Clustering and prediction of disease progression trajectories in Huntington's disease: An analysis of Enroll-HD data using a machine learning approach

INTRODUCTION: Huntington's disease (HD) is a rare neurodegenerative disease characterized by cognitive, behavioral and motor symptoms that progressively worsen with time. Cognitive and behavioral signs of HD are generally present in the years prior to a diagnosis; however, manifest HD is typica...

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Detalles Bibliográficos
Autores principales: Ko, Jinnie, Furby, Hannah, Ma, Xiaoye, Long, Jeffrey D., Lu, Xiao-Yu, Slowiejko, Diana, Gandhy, Rita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9923354/
https://www.ncbi.nlm.nih.gov/pubmed/36793800
http://dx.doi.org/10.3389/fneur.2022.1034269

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