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Anticancer and Biological Effects of Some Natural Compounds and Theoretical Investigation of them Against RdRP of SARS-COV-2: In Silico and In Vitro Studies

In this study, Skullcapflavone I and Skullcapflavone II molecules showed good inhibitory activities against α-glucosidase and sorbitol dehydrogenase enzymes with IC50 values of 102.66 ± 8.43 and 95.04 ± 11.52 nM for α-glucosidase and 38.42 ± 3.82 and 28.81 ± 3.26 µM for sorbitol dehydrogenase. The c...

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Detalles Bibliográficos
Autores principales: Zhang, Jing, Feng, Jingyu, Li, Yang, Wang, Jiguo, Mo, Panyan, Luo, Changguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9923641/
https://www.ncbi.nlm.nih.gov/pubmed/36780057
http://dx.doi.org/10.1007/s12033-023-00678-2