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Differential requirement of neutralizing antibodies and T cells on protective immunity to SARS-CoV-2 variants of concern

The current COVID-19 vaccines protect against severe disease, but are not effective in controlling replication of the Variants of Concern (VOCs). Here, we used the existing pre-clinical models of severe and moderate COVID-19 to evaluate the efficacy of a Spike-based DNA vaccine (pCTV-WS) for protect...

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Detalles Bibliográficos
Autores principales:	Azevedo, Patrick O., Hojo-Souza, Natália S., Faustino, Lídia P., Fumagalli, Marcílio J., Hirako, Isabella C., Oliveira, Emiliano R., Figueiredo, Maria M., Carvalho, Alex F., Doro, Daniel, Benevides, Luciana, Durigon, Edison, Fonseca, Flávio, Machado, Alexandre M., Fernandes, Ana P., Teixeira, Santuza R., Silva, João S., Gazzinelli, Ricardo T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9923671/ https://www.ncbi.nlm.nih.gov/pubmed/36781862 http://dx.doi.org/10.1038/s41541-023-00616-y

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