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Relapsed primary extraskeletal osteosarcoma of liver: A case report and review of literature

BACKGROUND: Extraskeletal osteosarcoma (ESOS) is a highly malignant osteosarcoma that occurs in extraskeletal tissues. It often affects the soft tissues of the limbs. ESOS is classified as primary or secondary. Here, we report a case of primary hepatic osteosarcoma in a 76-year-old male patient, whi...

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Autores principales: Di, Qiu-Yi, Long, Xiang-Dang, Ning, Jing, Chen, Zhi-Hong, Mao, Zhi-Qun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9923861/
https://www.ncbi.nlm.nih.gov/pubmed/36793644
http://dx.doi.org/10.12998/wjcc.v11.i3.662
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author Di, Qiu-Yi
Long, Xiang-Dang
Ning, Jing
Chen, Zhi-Hong
Mao, Zhi-Qun
author_facet Di, Qiu-Yi
Long, Xiang-Dang
Ning, Jing
Chen, Zhi-Hong
Mao, Zhi-Qun
author_sort Di, Qiu-Yi
collection PubMed
description BACKGROUND: Extraskeletal osteosarcoma (ESOS) is a highly malignant osteosarcoma that occurs in extraskeletal tissues. It often affects the soft tissues of the limbs. ESOS is classified as primary or secondary. Here, we report a case of primary hepatic osteosarcoma in a 76-year-old male patient, which is very rare. CASE SUMMARY: Here, we report a case of primary hepatic osteosarcoma in a 76-year-old male patient. The patient had a giant cystic-solid mass in the right hepatic lobe that was evident on ultrasound and computed tomography. Postoperative pathology and immunohistochemistry of the mass, which was surgically removed, suggested fibroblastic osteosarcoma. Hepatic osteosarcoma reoccurred 48 d after surgery, resulting in significant compression and narrowing of the hepatic segment of the inferior vena cava. Consequently, the patient underwent stent implantation in the inferior vena cava and transcatheter arterial chemoembolization. Unfortunately, the patient died of multiple organ failure postoperatively. CONCLUSION: ESOS is a rare mesenchymal tumor with a short course and a high likelihood of metastasis and recurrence. The combination of surgical resection and chemotherapy may be the best treatment.
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spelling pubmed-99238612023-02-14 Relapsed primary extraskeletal osteosarcoma of liver: A case report and review of literature Di, Qiu-Yi Long, Xiang-Dang Ning, Jing Chen, Zhi-Hong Mao, Zhi-Qun World J Clin Cases Case Report BACKGROUND: Extraskeletal osteosarcoma (ESOS) is a highly malignant osteosarcoma that occurs in extraskeletal tissues. It often affects the soft tissues of the limbs. ESOS is classified as primary or secondary. Here, we report a case of primary hepatic osteosarcoma in a 76-year-old male patient, which is very rare. CASE SUMMARY: Here, we report a case of primary hepatic osteosarcoma in a 76-year-old male patient. The patient had a giant cystic-solid mass in the right hepatic lobe that was evident on ultrasound and computed tomography. Postoperative pathology and immunohistochemistry of the mass, which was surgically removed, suggested fibroblastic osteosarcoma. Hepatic osteosarcoma reoccurred 48 d after surgery, resulting in significant compression and narrowing of the hepatic segment of the inferior vena cava. Consequently, the patient underwent stent implantation in the inferior vena cava and transcatheter arterial chemoembolization. Unfortunately, the patient died of multiple organ failure postoperatively. CONCLUSION: ESOS is a rare mesenchymal tumor with a short course and a high likelihood of metastasis and recurrence. The combination of surgical resection and chemotherapy may be the best treatment. Baishideng Publishing Group Inc 2023-01-26 2023-01-26 /pmc/articles/PMC9923861/ /pubmed/36793644 http://dx.doi.org/10.12998/wjcc.v11.i3.662 Text en ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. https://creativecommons.org/licenses/by-nc/4.0/This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
spellingShingle Case Report
Di, Qiu-Yi
Long, Xiang-Dang
Ning, Jing
Chen, Zhi-Hong
Mao, Zhi-Qun
Relapsed primary extraskeletal osteosarcoma of liver: A case report and review of literature
title Relapsed primary extraskeletal osteosarcoma of liver: A case report and review of literature
title_full Relapsed primary extraskeletal osteosarcoma of liver: A case report and review of literature
title_fullStr Relapsed primary extraskeletal osteosarcoma of liver: A case report and review of literature
title_full_unstemmed Relapsed primary extraskeletal osteosarcoma of liver: A case report and review of literature
title_short Relapsed primary extraskeletal osteosarcoma of liver: A case report and review of literature
title_sort relapsed primary extraskeletal osteosarcoma of liver: a case report and review of literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9923861/
https://www.ncbi.nlm.nih.gov/pubmed/36793644
http://dx.doi.org/10.12998/wjcc.v11.i3.662
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