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Loss of tumor suppressor menin expression in high grade cholangiocarcinomas

BACKGROUND: MEN1, which codes for the protein menin, is a tumor suppressor in neuroendocrine tissue. In cholangiocarcinoma (CCA) cell lines the overexpression of menin decreased proliferation, angiogenesis, migration, and invasion in vitro and in xenografts, but its expression in CCA tumor tissue sa...

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Detalles Bibliográficos
Autores principales:	Lairmore, Terry C., Abdulsattar, Jehan, De Benedetti, Arrigo, Shi, Runhua, Huang, Shile, Khalil, Md Imtiaz, Witt, Stephan N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research Note
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9923918/ https://www.ncbi.nlm.nih.gov/pubmed/36782257 http://dx.doi.org/10.1186/s13104-023-06282-6

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