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COVID-19 Vaccine-Induced Latent Autoimmune Diabetes in Adults

Since 2019, COVID-19 has plagued the world with its unfortunate death toll; however, with the introduction of multiple COVID vaccines, mortality and morbidity rates have severely declined. There have been misconceptions surrounding these vaccines, and at the same time, many documented conditions pre...

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Autores principales: Bally, Klynt, Ji, Beisi, Soni, Lina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9924027/
https://www.ncbi.nlm.nih.gov/pubmed/36793809
http://dx.doi.org/10.7759/cureus.33762
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author Bally, Klynt
Ji, Beisi
Soni, Lina
author_facet Bally, Klynt
Ji, Beisi
Soni, Lina
author_sort Bally, Klynt
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description Since 2019, COVID-19 has plagued the world with its unfortunate death toll; however, with the introduction of multiple COVID vaccines, mortality and morbidity rates have severely declined. There have been misconceptions surrounding these vaccines, and at the same time, many documented conditions precipitated by the vaccines. This case highlights a speculated relationship between new-onset Latent Autoimmune Diabetes in Adults (LADA) (presenting with diabetic ketoacidosis) and the COVID-19 vaccine. There have been articles suggesting the precipitation of diabetic ketoacidosis /hyperosmolar hyperglycemic syndrome, as well as new-onset diabetes mellitus (DM) with the COVID-19 vaccines but no documented link between LADA and the vaccine. The endpoint of this case is not only to highlight a newfound side-effect of the vaccine but also to urge primary care providers and physicians to closely monitor glucose levels and patient’s A1C after vaccine administration to prevent the formation of these hyperglycemic crises, as well as to consider autoimmune conditions in the differential diagnosis post-vaccination.
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spelling pubmed-99240272023-02-14 COVID-19 Vaccine-Induced Latent Autoimmune Diabetes in Adults Bally, Klynt Ji, Beisi Soni, Lina Cureus Endocrinology/Diabetes/Metabolism Since 2019, COVID-19 has plagued the world with its unfortunate death toll; however, with the introduction of multiple COVID vaccines, mortality and morbidity rates have severely declined. There have been misconceptions surrounding these vaccines, and at the same time, many documented conditions precipitated by the vaccines. This case highlights a speculated relationship between new-onset Latent Autoimmune Diabetes in Adults (LADA) (presenting with diabetic ketoacidosis) and the COVID-19 vaccine. There have been articles suggesting the precipitation of diabetic ketoacidosis /hyperosmolar hyperglycemic syndrome, as well as new-onset diabetes mellitus (DM) with the COVID-19 vaccines but no documented link between LADA and the vaccine. The endpoint of this case is not only to highlight a newfound side-effect of the vaccine but also to urge primary care providers and physicians to closely monitor glucose levels and patient’s A1C after vaccine administration to prevent the formation of these hyperglycemic crises, as well as to consider autoimmune conditions in the differential diagnosis post-vaccination. Cureus 2023-01-14 /pmc/articles/PMC9924027/ /pubmed/36793809 http://dx.doi.org/10.7759/cureus.33762 Text en Copyright © 2023, Bally et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Endocrinology/Diabetes/Metabolism
Bally, Klynt
Ji, Beisi
Soni, Lina
COVID-19 Vaccine-Induced Latent Autoimmune Diabetes in Adults
title COVID-19 Vaccine-Induced Latent Autoimmune Diabetes in Adults
title_full COVID-19 Vaccine-Induced Latent Autoimmune Diabetes in Adults
title_fullStr COVID-19 Vaccine-Induced Latent Autoimmune Diabetes in Adults
title_full_unstemmed COVID-19 Vaccine-Induced Latent Autoimmune Diabetes in Adults
title_short COVID-19 Vaccine-Induced Latent Autoimmune Diabetes in Adults
title_sort covid-19 vaccine-induced latent autoimmune diabetes in adults
topic Endocrinology/Diabetes/Metabolism
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9924027/
https://www.ncbi.nlm.nih.gov/pubmed/36793809
http://dx.doi.org/10.7759/cureus.33762
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