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β-Cyclodextrin: a green supramolecular catalyst assisted eco-friendly one-pot three-component synthesis of biologically active substituted pyrrolidine-2-one

A green, novel and eco-efficient synthetic route towards the synthesis of highly substituted bio-active pyrrolidine-2-one derivatives was demonstrated using β-cyclodextrin, a water-soluble supramolecular solid as a green and eco-benign catalyst at room temperature under water–ethanol solvent medium....

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Autores principales: Paul, Subhankar, Das, Sharmistha, Mitra, Bijeta, Chandra Pariyar, Gyan, Ghosh, Pranab
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9924053/
https://www.ncbi.nlm.nih.gov/pubmed/36793299
http://dx.doi.org/10.1039/d2ra08054k
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author Paul, Subhankar
Das, Sharmistha
Mitra, Bijeta
Chandra Pariyar, Gyan
Ghosh, Pranab
author_facet Paul, Subhankar
Das, Sharmistha
Mitra, Bijeta
Chandra Pariyar, Gyan
Ghosh, Pranab
author_sort Paul, Subhankar
collection PubMed
description A green, novel and eco-efficient synthetic route towards the synthesis of highly substituted bio-active pyrrolidine-2-one derivatives was demonstrated using β-cyclodextrin, a water-soluble supramolecular solid as a green and eco-benign catalyst at room temperature under water–ethanol solvent medium. The exploration of the green catalyst β-cyclodextrin for the metal-free one-pot three-component synthesis of a wide range of highly functionalized bio-active heterocyclic pyrrolidine-2-one moieties from easily available aldehydes and amines explains the superiority and uniqueness of this protocol.
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spelling pubmed-99240532023-02-14 β-Cyclodextrin: a green supramolecular catalyst assisted eco-friendly one-pot three-component synthesis of biologically active substituted pyrrolidine-2-one Paul, Subhankar Das, Sharmistha Mitra, Bijeta Chandra Pariyar, Gyan Ghosh, Pranab RSC Adv Chemistry A green, novel and eco-efficient synthetic route towards the synthesis of highly substituted bio-active pyrrolidine-2-one derivatives was demonstrated using β-cyclodextrin, a water-soluble supramolecular solid as a green and eco-benign catalyst at room temperature under water–ethanol solvent medium. The exploration of the green catalyst β-cyclodextrin for the metal-free one-pot three-component synthesis of a wide range of highly functionalized bio-active heterocyclic pyrrolidine-2-one moieties from easily available aldehydes and amines explains the superiority and uniqueness of this protocol. The Royal Society of Chemistry 2023-02-13 /pmc/articles/PMC9924053/ /pubmed/36793299 http://dx.doi.org/10.1039/d2ra08054k Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Paul, Subhankar
Das, Sharmistha
Mitra, Bijeta
Chandra Pariyar, Gyan
Ghosh, Pranab
β-Cyclodextrin: a green supramolecular catalyst assisted eco-friendly one-pot three-component synthesis of biologically active substituted pyrrolidine-2-one
title β-Cyclodextrin: a green supramolecular catalyst assisted eco-friendly one-pot three-component synthesis of biologically active substituted pyrrolidine-2-one
title_full β-Cyclodextrin: a green supramolecular catalyst assisted eco-friendly one-pot three-component synthesis of biologically active substituted pyrrolidine-2-one
title_fullStr β-Cyclodextrin: a green supramolecular catalyst assisted eco-friendly one-pot three-component synthesis of biologically active substituted pyrrolidine-2-one
title_full_unstemmed β-Cyclodextrin: a green supramolecular catalyst assisted eco-friendly one-pot three-component synthesis of biologically active substituted pyrrolidine-2-one
title_short β-Cyclodextrin: a green supramolecular catalyst assisted eco-friendly one-pot three-component synthesis of biologically active substituted pyrrolidine-2-one
title_sort β-cyclodextrin: a green supramolecular catalyst assisted eco-friendly one-pot three-component synthesis of biologically active substituted pyrrolidine-2-one
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9924053/
https://www.ncbi.nlm.nih.gov/pubmed/36793299
http://dx.doi.org/10.1039/d2ra08054k
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