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In Silico Discovery of Small Molecule Modulators Targeting the Achilles’ Heel of SARS-CoV-2 Spike Protein

[Image: see text] The spike protein of SARS-CoV-2 has been a promising target for developing vaccines and therapeutics due to its crucial role in the viral entry process. Previously reported cryogenic electron microscopy (cryo-EM) structures have revealed that free fatty acids (FFA) bind with SARS-C...

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Detalles Bibliográficos
Autores principales: Wang, Qing, Meng, Fanhao, Xie, Yuting, Wang, Wei, Meng, Yumin, Li, Linjie, Liu, Tao, Qi, Jianxun, Ni, Xiaodan, Zheng, Sanduo, Huang, Jianhui, Huang, Niu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9924089/
https://www.ncbi.nlm.nih.gov/pubmed/36844485
http://dx.doi.org/10.1021/acscentsci.2c01190