IFITM proteins assist cellular uptake of diverse linked chemotypes

The search for cell permeable drugs has conventionally focused on low molecular weight, non-polar, and rigid chemical structures. However, emerging therapeutic strategies break traditional drug design rules by employing flexibly linked chemical entities composed of more than one ligand. Using comple...

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Detalles Bibliográficos
Autores principales: Lou, Kevin, Wassarman, Douglas R., Yang, Tangpo, Paung, YiTing, Zhang, Ziyang, O’Loughlin, Thomas A., Moore, Megan K., Egan, Regina K., Greninger, Patricia, Benes, Cyril H., Seeliger, Markus A., Taunton, Jack, Gilbert, Luke A., Shokat, Kevan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9924227/
https://www.ncbi.nlm.nih.gov/pubmed/36480603
http://dx.doi.org/10.1126/science.abl5829

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