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Anti-Proliferative Effect of Potential LSD1/CoREST Inhibitors Based on Molecular Dynamics Model for Treatment of SH-SY5Y Neuroblastoma Cancer Cell Line

BACKGROUND: Lysine-specific demethylase is a demethylase enzyme that can remove methyl groups from histones H3K4me1/2 and H3K9me1/2. It is expressed in many cancers, where it impedes differentiation and contributes to cancer cell proliferation, cell metastasis and invasiveness, and is associated wit...

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Detalles Bibliográficos
Autores principales:	Zalloum, Hiba, Zalloum, Waleed, Hameduh, Tareq, AL Salamat, Husam, Zihlif, Malek
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	West Asia Organization for Cancer Prevention 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9924312/ https://www.ncbi.nlm.nih.gov/pubmed/36308380 http://dx.doi.org/10.31557/APJCP.2022.23.10.3533

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