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Dasabuvir suppresses esophageal squamous cell carcinoma growth in vitro and in vivo through targeting ROCK1

Esophageal squamous cell carcinoma (ESCC) is an upper gastrointestinal cancer with high morbidity and mortality. New strategies are urgently needed to prolong patients’ survival. Through screening FDA-approved drugs, we found dasabuvir, a drug approved for hepatitis C virus (HCV) treatment, suppress...

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Detalles Bibliográficos
Autores principales: Liu, Xinning, Jiang, Yanan, Zhou, Hao, Zhao, Xiaokun, Li, Mingzhu, Bao, Zhuo, Wang, Zitong, Zhang, Chenyang, Xie, Zhenliang, Zhao, Jimin, Dong, Zigang, Liu, Kangdong, Guo, Zhiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9924867/
https://www.ncbi.nlm.nih.gov/pubmed/36781836
http://dx.doi.org/10.1038/s41419-023-05633-2

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