Cargando…

Methemoglobinemia due to Hemolysis Secondary to Infection in a Child: A Case Report

Methemoglobinemia is a rare condition characterised by hypoxic state manifesting as headache, nausea, fatigue, and confusion. We report a 2-year-old boy presenting with fever and cough for 7 days with an episode of hypoxia as the saturation declined and did not improve on face mask oxygenation. On f...

Descripción completa

Detalles Bibliográficos
Autores principales: Parajuli, Biraj, Shrestha, Swikriti, Lamichhane, Sandesh, Subedi, Subash, KC, Sujata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Journal of the Nepal Medical Association 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9924921/
https://www.ncbi.nlm.nih.gov/pubmed/36705148
http://dx.doi.org/10.31729/jnma.7874
_version_ 1784887954083151872
author Parajuli, Biraj
Shrestha, Swikriti
Lamichhane, Sandesh
Subedi, Subash
KC, Sujata
author_facet Parajuli, Biraj
Shrestha, Swikriti
Lamichhane, Sandesh
Subedi, Subash
KC, Sujata
author_sort Parajuli, Biraj
collection PubMed
description Methemoglobinemia is a rare condition characterised by hypoxic state manifesting as headache, nausea, fatigue, and confusion. We report a 2-year-old boy presenting with fever and cough for 7 days with an episode of hypoxia as the saturation declined and did not improve on face mask oxygenation. On further evaluation, acute intravascular hemolysis was established following decreased haemoglobin level, increased levels of lactate dehydrogenase, and unconjugated bilirubin in the setting of documented infection. Assessment of arterial blood gas showed a significantly raised saturation gap and detection of methemoglobin confirmed the diagnosis. He was managed conservatively with packed red blood cells transfusion following which hypoxia was corrected. Methemoglobinemia as a result of hemolysis can be a non-cardio-respiratory cause of hypoxia and inciting aetiology needs to be addressed.
format Online
Article
Text
id pubmed-9924921
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Journal of the Nepal Medical Association
record_format MEDLINE/PubMed
spelling pubmed-99249212023-02-14 Methemoglobinemia due to Hemolysis Secondary to Infection in a Child: A Case Report Parajuli, Biraj Shrestha, Swikriti Lamichhane, Sandesh Subedi, Subash KC, Sujata JNMA J Nepal Med Assoc Case Report Methemoglobinemia is a rare condition characterised by hypoxic state manifesting as headache, nausea, fatigue, and confusion. We report a 2-year-old boy presenting with fever and cough for 7 days with an episode of hypoxia as the saturation declined and did not improve on face mask oxygenation. On further evaluation, acute intravascular hemolysis was established following decreased haemoglobin level, increased levels of lactate dehydrogenase, and unconjugated bilirubin in the setting of documented infection. Assessment of arterial blood gas showed a significantly raised saturation gap and detection of methemoglobin confirmed the diagnosis. He was managed conservatively with packed red blood cells transfusion following which hypoxia was corrected. Methemoglobinemia as a result of hemolysis can be a non-cardio-respiratory cause of hypoxia and inciting aetiology needs to be addressed. Journal of the Nepal Medical Association 2022-10 2022-10-31 /pmc/articles/PMC9924921/ /pubmed/36705148 http://dx.doi.org/10.31729/jnma.7874 Text en © The Author(s) 2018. https://creativecommons.org/licenses/by/4.0/This is an Open-Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Parajuli, Biraj
Shrestha, Swikriti
Lamichhane, Sandesh
Subedi, Subash
KC, Sujata
Methemoglobinemia due to Hemolysis Secondary to Infection in a Child: A Case Report
title Methemoglobinemia due to Hemolysis Secondary to Infection in a Child: A Case Report
title_full Methemoglobinemia due to Hemolysis Secondary to Infection in a Child: A Case Report
title_fullStr Methemoglobinemia due to Hemolysis Secondary to Infection in a Child: A Case Report
title_full_unstemmed Methemoglobinemia due to Hemolysis Secondary to Infection in a Child: A Case Report
title_short Methemoglobinemia due to Hemolysis Secondary to Infection in a Child: A Case Report
title_sort methemoglobinemia due to hemolysis secondary to infection in a child: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9924921/
https://www.ncbi.nlm.nih.gov/pubmed/36705148
http://dx.doi.org/10.31729/jnma.7874
work_keys_str_mv AT parajulibiraj methemoglobinemiaduetohemolysissecondarytoinfectioninachildacasereport
AT shresthaswikriti methemoglobinemiaduetohemolysissecondarytoinfectioninachildacasereport
AT lamichhanesandesh methemoglobinemiaduetohemolysissecondarytoinfectioninachildacasereport
AT subedisubash methemoglobinemiaduetohemolysissecondarytoinfectioninachildacasereport
AT kcsujata methemoglobinemiaduetohemolysissecondarytoinfectioninachildacasereport