Senolytic drugs, dasatinib and quercetin, attenuate adipose tissue inflammation, and ameliorate metabolic function in old age

Aging results in an elevated burden of senescent cells, senescence‐associated secretory phenotype (SASP), and tissue infiltration of immune cells contributing to chronic low‐grade inflammation and a host of age‐related diseases. Recent evidence suggests that the clearance of senescent cells alleviat...

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Detalles Bibliográficos
Autores principales: Islam, Md Torikul, Tuday, Eric, Allen, Shanena, Kim, John, Trott, Daniel W., Holland, William L., Donato, Anthony J., Lesniewski, Lisa A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9924942/
https://www.ncbi.nlm.nih.gov/pubmed/36637079
http://dx.doi.org/10.1111/acel.13767

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9924942/
https://www.ncbi.nlm.nih.gov/pubmed/36637079
http://dx.doi.org/10.1111/acel.13767

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