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Chronic alcohol metabolism results in DNA repair infidelity and cell cycle‐induced senescence in neurons

Chronic binge‐like drinking is a risk factor for age‐related dementia, however, the lasting and irreversible effect of alcohol on the brain remains elusive. Transcriptomic changes in brain cortices revealed pro‐ageing hallmarks upon chronic ethanol exposure and these changes predominantly occur in n...

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Detalles Bibliográficos
Autores principales: Sun, Jacquelyne Ka‐Li, Wu, Deng, Wong, Genper Chi‐Ngai, Lau, Tsun‐Ming, Yang, Meigui, Hart, Ronald P., Kwan, Kin‐Ming, Chan, Ho Yin Edwin, Chow, Hei‐Man
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9924945/
https://www.ncbi.nlm.nih.gov/pubmed/36691110
http://dx.doi.org/10.1111/acel.13772