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Multiple hepatic and osseous focal lesions without splenomegaly and/or lymph nodes enlargement
BACKGROUND: Hepatic involvement is a common extranodal manifestation of common and some rare hematologic malignancies. Although the imaging features of more common hepatic diseases such as hepatocellular carcinoma, metastases, and infection may overlap with those of hepatic hematologic malignancies,...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9925213/ https://www.ncbi.nlm.nih.gov/pubmed/36818544 http://dx.doi.org/10.1186/s43066-023-00240-4 |
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author | Elghannam, Maged T. Hassanien, Moataz H. Ameen, Yosry A. ELattar, Gamal M. ELRay, Ahmed A. ELtalkawy, Mohammed D. Montasser, Ahmed Y. |
author_facet | Elghannam, Maged T. Hassanien, Moataz H. Ameen, Yosry A. ELattar, Gamal M. ELRay, Ahmed A. ELtalkawy, Mohammed D. Montasser, Ahmed Y. |
author_sort | Elghannam, Maged T. |
collection | PubMed |
description | BACKGROUND: Hepatic involvement is a common extranodal manifestation of common and some rare hematologic malignancies. Although the imaging features of more common hepatic diseases such as hepatocellular carcinoma, metastases, and infection may overlap with those of hepatic hematologic malignancies, combining the imaging features with clinical manifestations and laboratory findings can facilitate correct diagnosis. Imaging has an important role in the diagnosis of hepatic focal lesions. CASE PRESENTATION: A case presented with isolated multiple hepatic focal lesions without nodal or spleen enlargement diagnosed only by immunohistochemical study and turned out to be primary hepatic lymphoma (PHL). PHL is rare with roughly 100 described cases and accounts for less than 1% of all non-Hodgkin lymphomas. Osseous involvement adds more challenge to the diagnosis. CONCLUSION: Hepatologists must be aware of PHL as it may be confused with more common hepatic diseases, mainly multifocal HCC and/or hepatic metastasis. |
format | Online Article Text |
id | pubmed-9925213 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-99252132023-02-14 Multiple hepatic and osseous focal lesions without splenomegaly and/or lymph nodes enlargement Elghannam, Maged T. Hassanien, Moataz H. Ameen, Yosry A. ELattar, Gamal M. ELRay, Ahmed A. ELtalkawy, Mohammed D. Montasser, Ahmed Y. Egypt Liver J Case Report BACKGROUND: Hepatic involvement is a common extranodal manifestation of common and some rare hematologic malignancies. Although the imaging features of more common hepatic diseases such as hepatocellular carcinoma, metastases, and infection may overlap with those of hepatic hematologic malignancies, combining the imaging features with clinical manifestations and laboratory findings can facilitate correct diagnosis. Imaging has an important role in the diagnosis of hepatic focal lesions. CASE PRESENTATION: A case presented with isolated multiple hepatic focal lesions without nodal or spleen enlargement diagnosed only by immunohistochemical study and turned out to be primary hepatic lymphoma (PHL). PHL is rare with roughly 100 described cases and accounts for less than 1% of all non-Hodgkin lymphomas. Osseous involvement adds more challenge to the diagnosis. CONCLUSION: Hepatologists must be aware of PHL as it may be confused with more common hepatic diseases, mainly multifocal HCC and/or hepatic metastasis. Springer Berlin Heidelberg 2023-02-13 2023 /pmc/articles/PMC9925213/ /pubmed/36818544 http://dx.doi.org/10.1186/s43066-023-00240-4 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Case Report Elghannam, Maged T. Hassanien, Moataz H. Ameen, Yosry A. ELattar, Gamal M. ELRay, Ahmed A. ELtalkawy, Mohammed D. Montasser, Ahmed Y. Multiple hepatic and osseous focal lesions without splenomegaly and/or lymph nodes enlargement |
title | Multiple hepatic and osseous focal lesions without splenomegaly and/or lymph nodes enlargement |
title_full | Multiple hepatic and osseous focal lesions without splenomegaly and/or lymph nodes enlargement |
title_fullStr | Multiple hepatic and osseous focal lesions without splenomegaly and/or lymph nodes enlargement |
title_full_unstemmed | Multiple hepatic and osseous focal lesions without splenomegaly and/or lymph nodes enlargement |
title_short | Multiple hepatic and osseous focal lesions without splenomegaly and/or lymph nodes enlargement |
title_sort | multiple hepatic and osseous focal lesions without splenomegaly and/or lymph nodes enlargement |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9925213/ https://www.ncbi.nlm.nih.gov/pubmed/36818544 http://dx.doi.org/10.1186/s43066-023-00240-4 |
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