Dynamic SUMOylation of MORC2 orchestrates chromatin remodelling and DNA repair in response to DNA damage and drives chemoresistance in breast cancer

Rationale: SUMOylation regulates a plethora of biological processes, and its inhibitors are currently under investigation in clinical trials as anticancer agents. Thus, identifying new targets with site-specific SUMOylation and defining their biological functions will not only provide new mechanisti...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Fang-Lin, Yang, Shao-Ying, Liao, Li, Zhang, Tai-Mei, Zhang, Yin-Ling, Hu, Shu-Yuan, Deng, Ling, Huang, Min-Ying, Andriani, Lisa, Ma, Xiao-Yan, Shao, Zhi-Min, Li, Da-Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9925317/
https://www.ncbi.nlm.nih.gov/pubmed/36793866
http://dx.doi.org/10.7150/thno.79688

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9925317/
https://www.ncbi.nlm.nih.gov/pubmed/36793866
http://dx.doi.org/10.7150/thno.79688

Ejemplares similares