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Hepatic PTP4A1 ameliorates high-fat diet-induced hepatosteatosis and hyperglycemia by the activation of the CREBH/FGF21 axis

Precise regulation of kinases and phosphatases is crucial for human metabolic homeostasis. This study aimed to investigate the roles and molecular mechanisms of protein tyrosine phosphatase type IVA1 (PTP4A1) in regulating hepatosteatosis and glucose homeostasis. Method: Ptp4a1(-/-) mice, adeno-asso...

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Detalles Bibliográficos
Autores principales:	Hwang, Byungtae, Kwon, Min-Gi, Cho, Min Ji, Lee, Nam-Kyung, Lee, Jangwook, Lee, Jeong Woong, Oh, Kyoung-Jin, Bae, Kwang-Hee, Hwang, Jung Hwan, Min, Jeong-Ki, Park, Jong-Gil
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2023
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9925322/ https://www.ncbi.nlm.nih.gov/pubmed/36793871 http://dx.doi.org/10.7150/thno.79434

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