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Effect of CYP2C19 polymorphisms on antidepressant prescription patterns and treatment emergent mania in bipolar disorder

Antidepressant medication is used extensively to treat bipolar depression despite uncertain efficacy. The cytochrome P450 (CYP) 2C19 enzyme metabolize several antidepressants, and polymorphisms in the corresponding gene CYP2C19 influence plasma concentration and hence treatment outcomes in major dep...

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Detalles Bibliográficos
Autores principales:	Joas, Erik, Jonsson, Lina, Viktorin, Alexander, Smedler, Erik, Pålsson, Erik, Goodwin, Guy M., Landén, Mikael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9925376/ https://www.ncbi.nlm.nih.gov/pubmed/36333412 http://dx.doi.org/10.1038/s41397-022-00294-4

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